Patent classifications
C07D219/08
COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOXIDANT AND/OR DYE
The invention relates to a compound, to a rubber mixture containing the compound, to a vehicle tire comprising the rubber mixture in at least one component, to a process for preparing the compound and to the use of the compound as aging stabilizer and/or antioxidant and/or dye.
The compound of the invention has the following formula I): I)
##STR00001## where R1 is selected from the group consisting of benzyl and linear, branched and cyclic aliphatic C3 to C12 radicals; and where the R4 and R5 radicals are independently the same or different and are each selected from the group consisting of linear, branched and cyclic aliphatic C1 to C12 radicals, and aryl radicals, cyano radicals, halogen radicals, preferably fluorine, bromine and chlorine, ester radicals, ketone radicals, ether radicals and thioether radicals, where the linear, branched and cyclic aliphatic C1 to C12 radicals and aryl radicals may bear substituents.
COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOZONANT AND/OR DYE
A compound, a rubber mixture containing the compound, a vehicle tire comprising the rubber mixture in at least one component, a process for producing the compound and the use of the compound as an aging stabilizer and/or antiozonant and/or dye, in which the compound has the following formula I):
##STR00001##
wherein R.sup.1 is selected from the group consisting of xi) aromatic radicals, wherein the aromatic radicals optionally bear substituents selected from the group consisting of halogen radicals, cyano radicals, ester radicals, ketone radicals, ether radicals and thioether radicals, and xii) linear, branched and cyclic aliphatic C.sub.4- to C.sub.12-radicals and xiii) combinations of aromatic and aliphatic C.sub.1- to C.sub.12-radicals.
Organic molecules for use in optoelectronic devices
The invention relates to an organic molecule having a structure of the formula I ##STR00001## where X=CN or CF.sub.3; D=chemical unit having a structure of the formula I-1: ##STR00002## where #=attachment point of the unit of formula I-1 to the central phenyl ring in the structure of formula I; A and B=independently of one another are selected from the group consisting of CRR.sup.1, CR, NR, N, there being a single or double bond between A and B and a single or double bond between B and Z; and Z=a direct bond or a divalent organic bridge which is a substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group or a combination thereof, CRR.sup.1, CCRR.sup.1, CNR, NR, O, SiRR.sup.1, S, S(O), S(O).sub.2, O-interrupted substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group, phenyl units or substituted phenyl units.
Organic molecules for use in optoelectronic devices
The invention relates to an organic molecule having a structure of the formula I ##STR00001## where X=CN or CF.sub.3; D=chemical unit having a structure of the formula I-1: ##STR00002## where #=attachment point of the unit of formula I-1 to the central phenyl ring in the structure of formula I; A and B=independently of one another are selected from the group consisting of CRR.sup.1, CR, NR, N, there being a single or double bond between A and B and a single or double bond between B and Z; and Z=a direct bond or a divalent organic bridge which is a substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group or a combination thereof, CRR.sup.1, CCRR.sup.1, CNR, NR, O, SiRR.sup.1, S, S(O), S(O).sub.2, O-interrupted substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group, phenyl units or substituted phenyl units.
COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PREPARING THE COMPOUND, AND USE OF THE COMPOUND AS AN ANTI-AGING AGENT AND/OR ANTIOXIDANT
A compound having the following formula I):
##STR00001## wherein R.sup.1 is selected from the group consisting of xi) aromatic radicals, wherein the aromatic radicals optionally bear substituents selected from the group consisting of halogen radicals, cyano radicals, ester radicals, ketone radicals, ether radicals and thioether radicals, and xii) linear, branched and cyclic aliphatic C.sub.3- to C.sub.12-radicals, wherein R.sup.1 is optionally a divalent radical bonded to the benzene ring with one valence; and wherein R.sup.2 is selected from the group consisting of linear, branched and cyclic aliphatic C.sub.1- to C.sub.12-radicals optionally bearing one or more halogen substituents, aryl radicals optionally bearing one or more halogen substituents and halogen radicals, wherein fluorine, bromine and chlorine are preferred, cyano radicals, ester radicals, ketone radicals, ether radicals and thioether radicals; and wherein m assumes the value 0 or 1 or 2 or 3.
COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PREPARING THE COMPOUND, AND USE OF THE COMPOUND AS AN ANTI-AGING AGENT AND/OR ANTIOXIDANT
A compound having the following formula I):
##STR00001## wherein R.sup.1 is selected from the group consisting of xi) aromatic radicals, wherein the aromatic radicals optionally bear substituents selected from the group consisting of halogen radicals, cyano radicals, ester radicals, ketone radicals, ether radicals and thioether radicals, and xii) linear, branched and cyclic aliphatic C.sub.3- to C.sub.12-radicals, wherein R.sup.1 is optionally a divalent radical bonded to the benzene ring with one valence; and wherein R.sup.2 is selected from the group consisting of linear, branched and cyclic aliphatic C.sub.1- to C.sub.12-radicals optionally bearing one or more halogen substituents, aryl radicals optionally bearing one or more halogen substituents and halogen radicals, wherein fluorine, bromine and chlorine are preferred, cyano radicals, ester radicals, ketone radicals, ether radicals and thioether radicals; and wherein m assumes the value 0 or 1 or 2 or 3.
NOVEL HDMX INHIBITORS AND THEIR USE FOR CANCER TREATMENT
The present invention provides for novel acridine-like class of compounds that have demonstrated efficiency in treating cancer. The compounds of the present invention have demonstrated efficacy in binding to and antagonizing the activity of the p53 repressor, HDMX. Once administered to a cell, the compounds of the present invention bind HDMX, thereby allowing p53 to induce apoptosis of the cancerous cell. A combination of this class of compounds along with Nutlin3 provides a novel approach to treat cancers.
DIAZONIUM COMPOUNDS AND METHODS OF USE FOR DNA CLEAVAGE
The present disclosure relates to aryl diazonium compounds and methods of cleaving DNA using the diazonium compounds as described herein. Further, the present disclosure relates to said aryl diazonium compounds conjugated to additional compounds as described herein.
DIAZONIUM COMPOUNDS AND METHODS OF USE FOR DNA CLEAVAGE
The present disclosure relates to aryl diazonium compounds and methods of cleaving DNA using the diazonium compounds as described herein. Further, the present disclosure relates to said aryl diazonium compounds conjugated to additional compounds as described herein.