Patent classifications
C
CHEMISTRY; METALLURGY
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C07
ORGANIC CHEMISTRY
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C07D
HETEROCYCLIC COMPOUNDS
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223/00
Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
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C07D223/14
condensed with carbocyclic rings or ring systems
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C07D223/18
Dibenzazepines; Hydrogenated dibenzazepines
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C07D223/18

Small molecule inhibitors of the ribosome biogenesis factor NVL2
20260097047 · 2026-04-09 · ·

Described are dibenzothiazepinone and dibenzazepinone-based compounds, methods for treating cancers with small molecule inhibitors of the ribosome biogenesis factor NVL2, related pharmaceutical compositions, methods to inhibit ribosome biogenesis or induce p53 or inhibit cancer cells and methods of screening for candidate therapeutics for treating cancer.

Small molecule inhibitors of the ribosome biogenesis factor NVL2
20260097047 · 2026-04-09 · ·

Described are dibenzothiazepinone and dibenzazepinone-based compounds, methods for treating cancers with small molecule inhibitors of the ribosome biogenesis factor NVL2, related pharmaceutical compositions, methods to inhibit ribosome biogenesis or induce p53 or inhibit cancer cells and methods of screening for candidate therapeutics for treating cancer.