Patent classifications
C07D231/06
Heterocyclic compounds as pesticides
The present application relates to the use of heterocyclic compounds for controlling animal pests including arthropods, insects and nematodes, to novel heterocyclic compounds, to processes for their preparation and to intermediates for preparing the heterocyclic compounds.
Small molecule inducers of autophagy
Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
Small molecule inducers of autophagy
Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers
The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, inflammatory disorders, cardiometabolic disorders, hepatic disorders, and/or cancers.
Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers
The present invention provides novel, diastereomeric pyrazolines that are useful as cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, inflammatory disorders, cardiometabolic disorders, hepatic disorders, and/or cancers.
BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM
A blue light blocking film layer and a blue light blocking system are disclosed. The system comprises at least one blue light blocking film layer, and a basal layer, and one or more optional release film layers, wherein,
the blue light blocking film layer is essential and includes at least a compound selected from formula (I-1), (II-1) and (II-2),
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BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM
A blue light blocking film layer and a blue light blocking system are disclosed. The system comprises at least one blue light blocking film layer, and a basal layer, and one or more optional release film layers, wherein,
the blue light blocking film layer is essential and includes at least a compound selected from formula (I-1), (II-1) and (II-2),
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Inhibitors of receptor interacting protein kinase I for the treatment of disease
Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
Inhibitors of receptor interacting protein kinase I for the treatment of disease
Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
The present disclosure provides compounds, pharmaceutical compositions, and methods for the treatment of cancer and fibrosis. The disclosed pharmaceutical compositions may include one or more pyrazolyl-containing compounds, or a derivative thereof.