Patent classifications
C07D239/04
Lithium-ion battery and apparatus
This application provides a lithium-ion battery and an apparatus. The lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode plate, a negative electrode plate, and a separator. A positive active material of the positive electrode plate includes Li.sub.x1Co.sub.y1M.sub.1-y1O.sub.2-z1Q.sub.z1, where 0.5x11.2, 0.8y1<1.0, 0z10.1, M is selected from one or more of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A, an additive B, and an additive C. The additive A is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential. The additive B is an anhydride compound. The additive C is a halogen substituted cyclic carbonate compound.
LITHIUM-ION BATTERY AND APPARATUS
This application provides a lithium-ion battery and an apparatus. The lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode plate, a negative electrode plate, and a separator. A positive active material of the positive electrode plate includes Li.sub.x1CO.sub.y1M.sub.1-y1O.sub.2-z1Q.sub.z1, where 0.5x11.2, 0.8y11.0, 0z10.1, M is selected from one or more of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A, an additive B, and an additive C. The additive A is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential. The additive B is an anhydride compound. The additive C is a halogen substituted cyclic carbonate compound.
LITHIUM-ION BATTERY AND APPARATUS
This application provides a lithium-ion battery and an apparatus. The lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode plate, a negative electrode plate, and a separator. A positive active material of the positive electrode plate includes Li.sub.x1CO.sub.y1M.sub.1-y1O.sub.2-z1Q.sub.z1, where 0.5x11.2, 0.8y11.0, 0z10.1, M is selected from one or more of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A, an additive B, and an additive C. The additive A is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential. The additive B is an anhydride compound. The additive C is a halogen substituted cyclic carbonate compound.
Electrolyte and electrochemical device
An electrolyte and an electrochemical device, which relates to the field of energy storage materials. The electrolyte includes an additive A, an additive B and an additive C, the additive A selected from a group consisting of multi-cyano six-membered N-heterocyclic compounds represented by Formula I-1, Formula I-2 or Formula I-3, and combinations thereof, the additive B is at least one sulfonate compound, and the additive C is at least one halogenated cyclic carbonate compound. The electrochemical device includes the above electrolyte. The electrolyte of the present disclosure can effectively passivate the surface activity of the positive electrode material, inhibit the oxidation of the electrolyte, and effectively reduce gas production of a battery, meanwhile the electrolyte can be also adsorbed catalytically active of the graphite surface to form a more stable SEI film, thereby effectively reducing side reactions ##STR00001##
Electrolyte and electrochemical device
An electrolyte and an electrochemical device, which relates to the field of energy storage materials. The electrolyte includes an additive A, an additive B and an additive C, the additive A selected from a group consisting of multi-cyano six-membered N-heterocyclic compounds represented by Formula I-1, Formula I-2 or Formula I-3, and combinations thereof, the additive B is at least one sulfonate compound, and the additive C is at least one halogenated cyclic carbonate compound. The electrochemical device includes the above electrolyte. The electrolyte of the present disclosure can effectively passivate the surface activity of the positive electrode material, inhibit the oxidation of the electrolyte, and effectively reduce gas production of a battery, meanwhile the electrolyte can be also adsorbed catalytically active of the graphite surface to form a more stable SEI film, thereby effectively reducing side reactions ##STR00001##
BUMETANIDE ANALOGS, COMPOSITIONS AND METHODS OF USE
The present invention provides bumetanide analogs and compositions comprising such analogs. The present invention also provides pharmaceutical compositions containing these bumetanide analogs and methods for their use. These analogs are believed useful for the treatment and/or prophylaxis of conditions that involve the Na.sup.+K.sup.+Cl.sup. co-transporter or GABA.sub.A receptor.
BUMETANIDE ANALOGS, COMPOSITIONS AND METHODS OF USE
The present invention provides bumetanide analogs and compositions comprising such analogs. The present invention also provides pharmaceutical compositions containing these bumetanide analogs and methods for their use. These analogs are believed useful for the treatment and/or prophylaxis of conditions that involve the Na.sup.+K.sup.+Cl.sup. co-transporter or GABA.sub.A receptor.
ANTIMICROBIAL COMPOSITION COMPRISING A POLYSACCHARIDE, A STABILIZING AGENT AND TRIIODIDE, METHOD OF PREPARATION THEREOF AND USE THEREOF
A composition having antimicrobial activity is provided. The composition comprises a polysaccharide, a stabilizer, and a triiodide, where the triiodide decomposition to iodide and volatile iodine can be significantly suppressed by the presence of the stabilizer. Methods of preparing and using the composition and devices prepared therewith are also disclosed. As compared to liquid forms comprising triiodide, stabilized solid forms can be used for a much wider range of applications due to their shape stability and a significantly smaller volume and weight of total material.
BTK inhibitor
- Xuehai Wang ,
- Chengde Wu ,
- Yong XU ,
- Chunli Shen ,
- Li'e Li ,
- Guoping Hu ,
- Yang Yue ,
- Jian Li ,
- Diliang Guo ,
- Nengyang Shi ,
- Lu Huang ,
- Shuhui Chen ,
- Ronghua Tu ,
- Zhongwen Yang ,
- Xuwen Zhang ,
- Qiang Xiao ,
- Hua Tian ,
- Yanping Yu ,
- Hailiang Chen ,
- Wenjie Sun ,
- Zhenyu He ,
- Jie Shen ,
- Jing Yang ,
- Jing Tang ,
- Wen Zhou ,
- Jing Yu ,
- Yi Zhang ,
- Quan Liu
Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV). ##STR00001##
BTK inhibitor
- Xuehai Wang ,
- Chengde Wu ,
- Yong XU ,
- Chunli Shen ,
- Li'e Li ,
- Guoping Hu ,
- Yang Yue ,
- Jian Li ,
- Diliang Guo ,
- Nengyang Shi ,
- Lu Huang ,
- Shuhui Chen ,
- Ronghua Tu ,
- Zhongwen Yang ,
- Xuwen Zhang ,
- Qiang Xiao ,
- Hua Tian ,
- Yanping Yu ,
- Hailiang Chen ,
- Wenjie Sun ,
- Zhenyu He ,
- Jie Shen ,
- Jing Yang ,
- Jing Tang ,
- Wen Zhou ,
- Jing Yu ,
- Yi Zhang ,
- Quan Liu
Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV). ##STR00001##