C07D239/20

SUBSTITUTED TETRACYCLINE COMPOUNDS
20250388531 · 2025-12-25 ·

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms.

Ionic-liquid-based formulations for the prevention or treatment of neurological diseases

The present disclosure relates to an ionic liquid (IL)-based formulation comprising inhibitors of NADPH oxidases enzymes (Nox's), preferably isoforms 1 and 4, in particular the specific inhibitor 3-cyclohexyl-5-(2,4-dihydroxybenzylidene)-1-methyl-2-thiohydantoin, for the treatment, therapy or prevention of neurological diseases, in particular Parkinson's diseases.

Ionic-liquid-based formulations for the prevention or treatment of neurological diseases

The present disclosure relates to an ionic liquid (IL)-based formulation comprising inhibitors of NADPH oxidases enzymes (Nox's), preferably isoforms 1 and 4, in particular the specific inhibitor 3-cyclohexyl-5-(2,4-dihydroxybenzylidene)-1-methyl-2-thiohydantoin, for the treatment, therapy or prevention of neurological diseases, in particular Parkinson's diseases.

Glutamine analogs

The invention relates to novel glutamine analogs, a composition containing the glutamine analogs and the use thereof.

Glutamine analogs

The invention relates to novel glutamine analogs, a composition containing the glutamine analogs and the use thereof.