Patent classifications
C07D249/08
CANNABINOID DERIVATIVES
This disclosure relates to cannabinoid derivatives having the structure of formula (I), pharmaceutical compositions comprising them, and methods of using the cannabinoid derivatives in treating or preventing a diseases associated with a cannabinoid receptor in subject in need thereof, wherein the cannabinoid receptor is one or more of CB1, CB2, 5HT1A, 5HT2A, GPR18, GPR55, GPR119, TRPV1, TRPV2, PPARγ or a μ-opioid receptor.
NAMPT MODULATORS
Provided are compounds of Formula (II) or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and p are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.
##STR00001##
NAMPT MODULATORS
Provided are compounds of Formula (II) or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, and p are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.
##STR00001##
CYCLOHEXYL SUBSTITUTED TRIAZOLES
The invention provides novel compounds having the general formula I
##STR00001##
wherein R.sup.1, R.sup.2 and R.sup.3 are as defined herein, compositions including the compounds and methods of using the compounds as V1a receptor modulators for treatment of conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior, social anxiety disorder, post-traumatic stress disorder (PTSD), brain edema in stroke or traumatic brain injury, and phase shift sleep disorders such as jetlag
CYCLOHEXYL SUBSTITUTED TRIAZOLES
The invention provides novel compounds having the general formula I
##STR00001##
wherein R.sup.1, R.sup.2 and R.sup.3 are as defined herein, compositions including the compounds and methods of using the compounds as V1a receptor modulators for treatment of conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior, social anxiety disorder, post-traumatic stress disorder (PTSD), brain edema in stroke or traumatic brain injury, and phase shift sleep disorders such as jetlag
Biphenyl Derivatives
The invention relates to a compound of formula (I) wherein R.sup.1—R.sup.3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
##STR00001##
Biphenyl Derivatives
The invention relates to a compound of formula (I) wherein R.sup.1—R.sup.3 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
##STR00001##
AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND INDUSTRIAL MATERIAL PROTECTION AGENT
Provided is a plant disease controlling agent that has low toxicity to humans and animals, that is excellent in handling safety, and that has an excellent controlling effect against a wide range of plant diseases and a high antimicrobial action against plant disease fungi. The present invention is a compound represented by general formula (I) below, or N-oxide or a pesticidally acceptable salt thereof: [Chem. 1]
##STR00001##
AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND INDUSTRIAL MATERIAL PROTECTION AGENT
Provided is a plant disease controlling agent that has low toxicity to humans and animals, that is excellent in handling safety, and that has an excellent controlling effect against a wide range of plant diseases and a high antimicrobial action against plant disease fungi. The present invention is a compound represented by general formula (I) below, or N-oxide or a pesticidally acceptable salt thereof: [Chem. 1]
##STR00001##
HERBICIDAL TRIAZOLES
Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof,
##STR00001##
wherein A, X and Y are as defined in the disclosure.
Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.