The present invention provides a pest control agent, acaricide or fungicide that contains, as the active ingredient thereof, at least one type of compound selected from the aryloxyurea compounds represented by formula (V) (wherein R.sup.1 to R.sup.5 each independently represents an alkyl group or the like, X is a halogen atom or the like, n is an integer of 0 to 5, and Z is an oxygen atom or sulfur atom) or salts thereof. ##STR00001##

The present invention provides a pest control agent, acaricide or fungicide that contains, as the active ingredient thereof, at least one type of compound selected from the aryloxyurea compounds represented by formula (V) (wherein R.sup.1 to R.sup.5 each independently represents an alkyl group or the like, X is a halogen atom or the like, n is an integer of 0 to 5, and Z is an oxygen atom or sulfur atom) or salts thereof. ##STR00001##

This invention relates to compounds that inhibit creatine transport and/or creatine kinase, pharmaceutical compositions including such compounds, and methods of utilizing such compounds and compositions for the treatment of cancer.

This invention relates to compounds that inhibit creatine transport and/or creatine kinase, pharmaceutical compositions including such compounds, and methods of utilizing such compounds and compositions for the treatment of cancer.

This invention provides a novel disubstituted 1,2,4-triazine compound or a pharmaceutically acceptable salt thereof, which has an aldosterone synthetase inhibitory activity and is useful for preventing and/or treating various diseases or conditions associated with aldosterone; a method for preparing it; use of it; as well as a pharmaceutical composition comprising it as an active ingredient. A compound of the general formula [I]:

##STR00001##

wherein R.sup.A is, for example, a group of the following formula (A-1):

##STR00002##

wherein ring A.sup.1 is, for example, a cycloalkyl group which may be substituted, and R.sup.B is, for example, a monocyclic cycloalkyl group,
or a pharmaceutically acceptable salt thereof.

Provided is a compound having a D-amino acid oxidase (DAAO) inhibitory action, and useful as for example, a prophylaxis and/or therapeutic agent for schizophrenia or neuropathic pain. The present inventors have studied a compound that inhibits DAAO, and confirm that a dihydroxy aromatic heterocyclic compound has a DAAO inhibitory action, and completed the present invention. That is, the dihydroxy aromatic heterocyclic compound of the present invention has a good DAAO inhibitory action, and can be used as a prophylaxis and/or therapeutic agent for, for example, schizophrenia or neuropathic pain.

The present invention includes name compounds of general formula (I): (I) in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein, methods for their preparation, pharmaceutical compositions and combinations comprising said compounds, and their use for the treatment of hyperproliferative diseases.

##STR00001##

The present invention includes name compounds of general formula (I): (I) in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein, methods for their preparation, pharmaceutical compositions and combinations comprising said compounds, and their use for the treatment of hyperproliferative diseases.

##STR00001##

The present disclosure provides compounds which are useful in the treatment of oncological disorders, more particularly arylimidamides useful in the treatment of leukemias. Exemplary compounds include an azole moiety connected to a phenoxy or pyridyloxy moiety via an alkylene chain, the phenoxy or pyridyloxy moiety attached to a benzimidamide or pyridylimidamide function.

The present invention includes name compounds of general formula (I): (I) in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein, methods for their preparation, pharmaceutical compositions and combinations comprising said compounds, and their use for the treatment of hyperproliferative diseases. ##STR00001##