C07D253/10

Crystalline forms of 4-ethoxy-n-(2-methoxyethyl)-n-methyl-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5, 1-f][1,2,4]triazin-2-yl)benzenesulfonamide

The present invention provides solid, crystalline forms of Compound I. Compound I has the structure: ##STR00001##
The invention further provides methods for treating, preventing, or reducing a disease or disorder in a subject in need thereof, the methods comprising administering to the subject an effective amount of a crystalline form of Compound I. The disease or disorder may include any chronic disease and/or cardiovascular condition related to or caused by high blood pressure.

New Coolants, and Preparations Containing Same

The present invention relates to novel physiological coolants, mixtures of coolants containing these novel agents, mixtures of the coolants with flavors, the use of these coolants, and articles and end preparations for the consumer containing the physiological coolants or mixtures of coolants.

New Coolants, and Preparations Containing Same

The present invention relates to novel physiological coolants, mixtures of coolants containing these novel agents, mixtures of the coolants with flavors, the use of these coolants, and articles and end preparations for the consumer containing the physiological coolants or mixtures of coolants.

Organic compounds and organic light emitting display device using the same

The present disclosure relates to an organic compound and an organic light emitting display device using the same wherein the organic compound is represented by Chemical Formula 1 and a display device using the organic compound. The organic compound represented by Chemical Formula 1 has excellent electron transport properties and durability and is used for an electron transport layer of an organic light emitting element, thereby lowering a driving voltage and improving the luminous efficiency and lifetime. ##STR00001## (In the above Chemical Formula 1, at least two of X.sub.1, X.sub.2 and X.sub.3 are N, Y.sub.1 and Y.sub.2 are each independently a substituted or unsubstituted phenylene group or a single bond, at least one of Ar.sub.1 and Ar.sub.2 is selected from a substituted or unsubstituted triazine group, a functional group represented by Chemical Formula 2 and a functional group represented by Chemical Formula 3.)

Organic compounds and organic light emitting display device using the same

The present disclosure relates to an organic compound and an organic light emitting display device using the same wherein the organic compound is represented by Chemical Formula 1 and a display device using the organic compound. The organic compound represented by Chemical Formula 1 has excellent electron transport properties and durability and is used for an electron transport layer of an organic light emitting element, thereby lowering a driving voltage and improving the luminous efficiency and lifetime. ##STR00001## (In the above Chemical Formula 1, at least two of X.sub.1, X.sub.2 and X.sub.3 are N, Y.sub.1 and Y.sub.2 are each independently a substituted or unsubstituted phenylene group or a single bond, at least one of Ar.sub.1 and Ar.sub.2 is selected from a substituted or unsubstituted triazine group, a functional group represented by Chemical Formula 2 and a functional group represented by Chemical Formula 3.)

Substituted pyrrolo[1,2-b]pyridazines and pyrrolo[2,1-f][1,2,4]triazines as Btk inhibitors

Provided are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein ring A, R.sup.3, R.sup.4, R.sup.5, R.sup.6, A.sup.1, B.sup.1, B.sup.2, Q.sup.1 and Q.sup.2 are as defined herein; and methods for their use and production. ##STR00001##