Patent classifications
C07D263/04
OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME
Provided are novel selective androgen receptor agonists, a preparation method thereof, and a pharmaceutical composition including the same at a pharmaceutically effective amount. The selective androgen receptor agonists according to the present invention act on androgen receptors to increase androgen activity, thereby being usefully applied as a therapeutic and prophylactic agent for diseases or conditions, of which symptoms may be improved or may respond to treatment by increased activities of androgen receptors, namely, a variety of hormone-related diseases in male and female, muscle wasting disorders, osteoporosis, etc.
OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME
Provided are novel selective androgen receptor agonists, a preparation method thereof, and a pharmaceutical composition including the same at a pharmaceutically effective amount. The selective androgen receptor agonists according to the present invention act on androgen receptors to increase androgen activity, thereby being usefully applied as a therapeutic and prophylactic agent for diseases or conditions, of which symptoms may be improved or may respond to treatment by increased activities of androgen receptors, namely, a variety of hormone-related diseases in male and female, muscle wasting disorders, osteoporosis, etc.
METHOD FOR RECOVERING POLYOL FROM POLYURETHANE WASTE
A method for recovering polyol from a polyurethane waste includes: subjecting the polyurethane waste to degradation using a degradation agent, and then removing the degradation agent to obtain a degradation product including an amine compound and a polyol compound; subjecting the degradation product and a treatment agent represented by Formula (I) to a reaction to obtain a reaction solution including a reaction product and the polyol compound, the reaction product being formed by reacting the amine compound in the degradation product with the treatment agent, the reaction product being in a liquid form at 20 C. to 40 C.; and subjecting the reaction solution to distillation to remove an unreacted portion of the treatment agent, thereby obtaining a polyol mixture including the reaction product and the polyol compound, wherein each of the substituents in Formula (I) is given the definitions as set forth in the Specification and Claims.
METHOD FOR RECOVERING POLYOL FROM POLYURETHANE WASTE
A method for recovering polyol from a polyurethane waste includes: subjecting the polyurethane waste to degradation using a degradation agent, and then removing the degradation agent to obtain a degradation product including an amine compound and a polyol compound; subjecting the degradation product and a treatment agent represented by Formula (I) to a reaction to obtain a reaction solution including a reaction product and the polyol compound, the reaction product being formed by reacting the amine compound in the degradation product with the treatment agent, the reaction product being in a liquid form at 20 C. to 40 C.; and subjecting the reaction solution to distillation to remove an unreacted portion of the treatment agent, thereby obtaining a polyol mixture including the reaction product and the polyol compound, wherein each of the substituents in Formula (I) is given the definitions as set forth in the Specification and Claims.
Processes for the preparation of deuterated D-serine
Disclosed are methods for preparing deuterated analogs of
Processes for the preparation of deuterated D-serine
Disclosed are methods for preparing deuterated analogs of
Method of fixating carbon dioxide to substituted oxazolidinones
A method of fixating carbon dioxide (CO.sub.2) to form a substituted oxazolidinone is described. The method includes mixing a metal-organic framework (MOF), at least one epoxide, and at least one aromatic amine to form a mixture. The method further includes contacting the mixture with a gas stream containing CO.sub.2 to react the CO.sub.2 in the gas stream with the epoxide and the aromatic amine to form a substituted oxazolidinone. The MOF is a MIL-68(In)X MOF. X is of formula (I): ##STR00001##
where at least one of R.sup.1 to R.sup.4 is an amine-containing group, and R.sup.1 to R.sup.4 are independently an amine-containing group or a hydrogen.
Method of fixating carbon dioxide to substituted oxazolidinones
A method of fixating carbon dioxide (CO.sub.2) to form a substituted oxazolidinone is described. The method includes mixing a metal-organic framework (MOF), at least one epoxide, and at least one aromatic amine to form a mixture. The method further includes contacting the mixture with a gas stream containing CO.sub.2 to react the CO.sub.2 in the gas stream with the epoxide and the aromatic amine to form a substituted oxazolidinone. The MOF is a MIL-68(In)X MOF. X is of formula (I): ##STR00001##
where at least one of R.sup.1 to R.sup.4 is an amine-containing group, and R.sup.1 to R.sup.4 are independently an amine-containing group or a hydrogen.