The invention relates to 2,5-disubstituted benzoxazole and benzothiazole derivatives of Formula (I)

##STR00001##

wherein L, X, Y, and ring (A) are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds may be useful for the prevention or treatment of diseases or disorders associated with impaired reactive oxygen species (ROS) production, and/or for the prevention or treatment of various fibrotic diseases.

In one aspect, there is provided a method of coupling a first aromatic compound having a fluorosulfonate substituent to a second aromatic compound having a boron-containing substituent. In another aspect, there is provided a method of coupling a first aromatic compound having a hydroxyl substituent to a second aromatic compound having a boron-containing substituent in a one-pot reaction.

##STR00001##

In one aspect, there is provided a method of coupling a first aromatic compound having a fluorosulfonate substituent to a second aromatic compound having a boron-containing substituent. In another aspect, there is provided a method of coupling a first aromatic compound having a hydroxyl substituent to a second aromatic compound having a boron-containing substituent in a one-pot reaction.

##STR00001##

A novel compound of the Chemical Formula 1 and an organic electroluminescent device including the compound are disclosed. The novel compound, when included in an organic material layer, preferably a light emitting layer, of an organic electroluminescent device, can improve luminous efficiency, driving voltage, lifetime and other properties of the organic electroluminescent device: ##STR00001##

The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.

The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.

A fused heterocyclic compound represented by formula (1) or an N-oxide thereof has an excellent control effect on pests: ##STR00001##
wherein A.sup.1 represents N or the like, A.sup.2 represents NR.sup.6 or the like, A.sup.3 represents CR.sup.12 or the like, R.sup.1 represents a C1 to C6 chain hydrocarbon group or the like, R.sup.2, R.sup.4 and R.sup.5 are the same or different and represent a C1 to C3 alkyl group optionally having one or more halogen atoms or the like, R.sup.3 represents a C1 to C6 chain hydrocarbon group or the like, R.sup.6 represents a C1 to C6 chain hydrocarbon group or the like, any one set of R.sup.9 and R.sup.10, R.sup.10 and R.sup.11, and R.sup.11 and R.sup.12 in R.sup.9, R.sup.10, R.sup.11 and R.sup.12, together with the carbon atoms to which they are bound, forms a ring, and n represents 0, 1 or 2.

Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.

Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.