The present disclosure relates to a plurality of host materials comprising at least one first host compound and at least one second host compound and an organic electroluminescent device comprising the same. By comprising the specific combination of the compound according to the present disclosure as host materials, an organic electroluminescent device having low driving voltage, high luminous efficiency, and long lifespan characteristics can be prepared.

The present disclosure relates to a plurality of host materials comprising at least one first host compound and at least one second host compound and an organic electroluminescent device comprising the same. By comprising the specific combination of the compound according to the present disclosure as host materials, an organic electroluminescent device having low driving voltage, high luminous efficiency, and long lifespan characteristics can be prepared.

An organic light emitting device having improved driving voltage, efficiency and lifetime. The device includes a light emitting layer including a compound of Chemical Formula 1 and a compound of Chemical Formula 2.

##STR00001##

wherein: X.sub.1 to X.sub.7 are each independently CR.sub.1 or N, provided that at least one of X.sub.1 to X.sub.7 is N; Ar.sub.1 and Ar.sub.2 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; any one of R and R.sub.1 to R.sub.6 is Chemical Formula 2A, and the rest are hydrogen, deuterium, or a substituted or unsubstituted C.sub.6-60 aryl:

##STR00002##

where Ar.sub.1 and Ar.sub.2 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S, and the other substituents are as defined in the specification.

An organic light emitting device having improved driving voltage, efficiency and lifetime. The device includes a light emitting layer including a compound of Chemical Formula 1 and a compound of Chemical Formula 2.

##STR00001##

wherein: X.sub.1 to X.sub.7 are each independently CR.sub.1 or N, provided that at least one of X.sub.1 to X.sub.7 is N; Ar.sub.1 and Ar.sub.2 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; any one of R and R.sub.1 to R.sub.6 is Chemical Formula 2A, and the rest are hydrogen, deuterium, or a substituted or unsubstituted C.sub.6-60 aryl:

##STR00002##

where Ar.sub.1 and Ar.sub.2 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S, and the other substituents are as defined in the specification.

Provided are small molecule inhibitors of ubiquitin specific protease 1 (USP1) activity and methods for their use in treating and characterizing cancers. The small molecule USP1 inhibitors of the invention are particularly useful in the treatment of cancers that are resistant to DNA cross-linking agents.

Enzyme substrates and associated technology of the present invention are provided. An enzyme substrate of the invention may comprise a biologically functional fluorescent dye and an enzyme-specific substrate moiety attached in such a way that the functionality of the functional dye is diminished. An enzymatic reaction may cleave at least a portion of the substrate moiety from the enzyme substrate to provide a more functional product dye. This product dye may be nonfluorescent or weakly fluorescent, in general, and relatively fluorescent, in a particular condition, such as when bound to a partner biological molecule or an assembly of partner biological molecules. An enzyme substrate of the present invention may thus be useful in fluorescence detection, and/or in any of a variety of useful applications, such as the detection of enzymatic activity in a cell-free system or in a living cell, the screening of drugs, or the diagnosis of disease.

Provided are a compound of Formula 1 that can improve the luminous efficiency, stability, and lifespan of an organic electronic element using the same, the organic electronic element and an electronic device thereof.

Provided are a compound of Formula 1 that can improve the luminous efficiency, stability, and lifespan of an organic electronic element using the same, the organic electronic element and an electronic device thereof.

Provided are a compound of Formula 1 that can improve the luminous efficiency, stability, and lifespan of an organic electronic element using the same, the organic electronic element and an electronic device thereof.

Provided are a compound of Formula 1 that can improve the luminous efficiency, stability, and lifespan of an organic electronic element using the same, the organic electronic element and an electronic device thereof.