The invention relates to anthracycline derivative compounds for treating tumor diseases, and related methods, compositions, and kits. ##STR00001##

This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine, serotonin, epinephrine or norepinephrine are provided as therapeutic agents for the treatment of depression or anxiety in a mammalian subject.

This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine, serotonin, epinephrine or norepinephrine are provided as therapeutic agents for the treatment of depression or anxiety in a mammalian subject.

The present invention provides, for example, a compound mentioned below as a medicament for treating or preventing the diseases induced by production, secretion or deposition of amyloid- proteins. A compound of the formula (I): ##STR00001##
wherein R.sup.1, R.sup.2a, R.sup.2b, R.sup.3, R.sup.4a, R.sup.4b, ring A and the dashed lines are defined in the specification,
its pharmaceutically acceptable salt or a solvate thereof.

The present invention provides, for example, a compound mentioned below as a medicament for treating or preventing the diseases induced by production, secretion or deposition of amyloid- proteins. A compound of the formula (I): ##STR00001##
wherein R.sup.1, R.sup.2a, R.sup.2b, R.sup.3, R.sup.4a, R.sup.4b, ring A and the dashed lines are defined in the specification,
its pharmaceutically acceptable salt or a solvate thereof.

In a production method for a hemiaminal compound, a compound represented by Formula (1), a compound represented by Formula (2), and an oxidizing agent are mixed. A hemiaminal compound represented by Formula (3) is obtained. In a production method for a heterocyclic compound, a hemiaminal compound is mixed with a base. ##STR00001##

In a production method for a hemiaminal compound, a compound represented by Formula (1), a compound represented by Formula (2), and an oxidizing agent are mixed. A hemiaminal compound represented by Formula (3) is obtained. In a production method for a heterocyclic compound, a hemiaminal compound is mixed with a base. ##STR00001##

Provided are compounds which are useful for controlling microorganisms in aqueous or water-containing systems or in systems which are exposed to moisture, including at elevated temperature. The antimicrobial compounds are of the formula I: ##STR00001##
wherein n, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and X are as defined herein.

Provided are compounds which are useful for controlling microorganisms in aqueous or water-containing systems or in systems which are exposed to moisture, including at elevated temperature. The antimicrobial compounds are of the formula I: ##STR00001##
wherein n, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and X are as defined herein.