Patent classifications
C07D275/03
NOVEL ISOTHIAZOLAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES
The present invention relates to novel isothiazolamide derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds for controlling harmful microorganisms in crop protection and in the protection of materials, especially for controlling fungi, preferably for controlling fungi in plants or plant seeds.
Eis inhibitors
Compounds and compositions are disclosed, which are useful as inhibitors of acetyltransferase Eis, a mediator of kanamycin resistance in Mycobacterium tuberculosis.
Eis inhibitors
Compounds and compositions are disclosed, which are useful as inhibitors of acetyltransferase Eis, a mediator of kanamycin resistance in Mycobacterium tuberculosis.
TEAD INHIBITORS
The present invention relates to a compound of formula (I)
##STR00001## wherein A, Z, L, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.33 are as defined in claim 1, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) possess utility as inhibitors of TEAD. The compounds are useful as medicaments in the treatment of diseases or conditions wherein inhibition of TEAD is desired, such as cancer and chronic pain.
TEAD INHIBITORS
The present invention relates to a compound of formula (I)
##STR00001## wherein A, Z, L, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.33 are as defined in claim 1, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) possess utility as inhibitors of TEAD. The compounds are useful as medicaments in the treatment of diseases or conditions wherein inhibition of TEAD is desired, such as cancer and chronic pain.
GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR120 receptor. Such compounds are represented by Formula (I) and Formula (II) as follows:
##STR00001##
wherein Y, R.sup.1, G, and Q are defined herein;
and
##STR00002##
wherein R.sup.11, R.sup.21, R.sup.41, R.sup.B1 and G.sup.1, are defined herein.
GPR120 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR120 receptor. Such compounds are represented by Formula (I) and Formula (II) as follows:
##STR00001##
wherein Y, R.sup.1, G, and Q are defined herein;
and
##STR00002##
wherein R.sup.11, R.sup.21, R.sup.41, R.sup.B1 and G.sup.1, are defined herein.
Novel isothiazolamides, processes for their preparation and their use as herbicides and/or plant growth regulators
The invention relates to the technical field of the herbicides and/or plant growth regulators. Specifically, the invention primarily relates to novel isothiazolamides, and compositions comprising said novel isothiazolamides. Further, the present invention relates to processes for the preparation said novel isothiazolamides and their use as herbicides and/or plant growth regulators.
Novel isothiazolamides, processes for their preparation and their use as herbicides and/or plant growth regulators
The invention relates to the technical field of the herbicides and/or plant growth regulators. Specifically, the invention primarily relates to novel isothiazolamides, and compositions comprising said novel isothiazolamides. Further, the present invention relates to processes for the preparation said novel isothiazolamides and their use as herbicides and/or plant growth regulators.
A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION
The present invention is that provided a synthesis method of a series of isothiazole oxime ether-containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV.
##STR00001##
The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.