Patent classifications
C07D295/037
CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE
The invention provides compounds, compositions, methods, and kits for the treatment of pain, itch, and neurogenic inflammation.
CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE
The invention provides compounds, compositions, methods, and kits for the treatment of pain, itch, and neurogenic inflammation.
Synthesis of ZSM-5
A molecular sieve having the framework structure of ZSM-5 is produced using one or more of 1,4-bis(N-pentylpyrrolidinium)butane dications, 1,5-bis(N-pentylpyrrolidinium)pentane dications, and 1,6-bis(N-pentylpyrrolidinium)hexane dications as a structure directing agent.
Synthesis of ZSM-5
A molecular sieve having the framework structure of ZSM-5 is produced using one or more of 1,4-bis(N-pentylpyrrolidinium)butane dications, 1,5-bis(N-pentylpyrrolidinium)pentane dications, and 1,6-bis(N-pentylpyrrolidinium)hexane dications as a structure directing agent.
IONIC LIQUID AND PLASTIC CRYSTAL
The present invention provides an ionic liquid or plastic crystal comprising an anion and a cation, the anion comprising [C(SO.sub.2F).sub.3].sup.−, and the cation comprising at least one member selected from the group consisting of 1-ethyl-3-methylimidazolium ([EMI].sup.+), N,N-diethyl-N-methyl-(2-methoxyethyl)ammonium ([DEME].sup.+), N-methyl-N-propylpyrrolidinium ([Py.sub.13].sup.+), N-methyl-N-propylpiperidinium ([PP.sub.13].sup.+), tetramethylammonium ([N.sub.1111].sup.+), tetraethylammonium ([N.sub.2222].sup.+), trimethylhexylammonium ([N.sub.6111].sup.+), triethylhexylammonium ([N.sub.6222].sup.+), N-methyl-ethylpyrrolidinium ([Py.sub.12].sup.+), 1-butyl-3-methylimidazolium ([C.sub.4mim].sup.+), and 1-hexyl-3-methylimidazolium ([C.sub.6mim].sup.+).
IONIC LIQUID ADDITIVE FOR LITHIUM-ION BATTERY
An ionic liquid additive for lithium-ion battery
An ionic liquid for adding to an electrolyte of a lithium-ion battery, the ionic liquid comprises a compound with a dual core structure having the general formula (I):
##STR00001## wherein each of cationic group X.sub.1 and X.sub.2 are heterocyclic aromatic and amine.
Methods for extraction, processing, and purification of a selected family of target compounds from cannabis
Disclosed are methods for separating, recovering, and purifying tetrahydrocannabinolic acid (THCA) salts from an organic solvent solution comprising a mixture of cannabinoids. The methods comprise solubilizing the mixture of cannabinoids in a selected C5-C7 hydrocarbon solvent, adding thereto a selected amine to thereby precipitate a THCA-amine salt therefrom, dissolving the recovered THCA-amine salt in a selected solvent and then adding thereto a selected antisolvent to thereby recrystallize a purified THCA-amine salt therefrom. The recrystallized THCA-amine salt may be decarboxylated to form a mixture of Δ9-tetrahydrocannabinol (Δ9-THC) and amine. The Δ9-THC amine mixture may be acidified to separate the amine from Δ9-THC. The recovered Δ9-THC may be concentrated to produce a highly purified Δ9-THC. Also disclosed are THCA-amine salts produced with amines selected from groups of diamines, amino alcohols, and tertiary amines.
CRYSTALLINE SALTS OF TIZOXANIDE AND 2-HYDROXY-N-(5-CHLORO-1,3-THIAZOL-2-YL)BENZAMIDE (RM-4848) WITH ETHANOLAMINE, MORPHOLINE, PROPANOLAMINE, PIPERAZINE AND N-METHYLPIPERAZINE
The present invention refers to: crystalline tizoxanide amine salts, such as e.g. the ethanolamine salt, the morpholine salt, the propanolamine salt, the piperazine salt and the N-methylpiperazine salt, crystalline amine salts of 2-hydroxy-N-(5-halo-1,3-thiazol-2-yl) benzamide derivatives, such as e.g. the 2-hydroxy-N-(5-chloro-1,3-thiazol-2-yl)benzamide (RM-4848), a method for preparing a tizoxanide amine salt from its prodrug nitazoxanide (NTZ), pharmaceutical compositions comprising tizoxanide amine salts, tizoxanide amine salts for use as an antiviral or antiparasitic agent.
CRYSTALLINE SALTS OF TIZOXANIDE AND 2-HYDROXY-N-(5-CHLORO-1,3-THIAZOL-2-YL)BENZAMIDE (RM-4848) WITH ETHANOLAMINE, MORPHOLINE, PROPANOLAMINE, PIPERAZINE AND N-METHYLPIPERAZINE
The present invention refers to: crystalline tizoxanide amine salts, such as e.g. the ethanolamine salt, the morpholine salt, the propanolamine salt, the piperazine salt and the N-methylpiperazine salt, crystalline amine salts of 2-hydroxy-N-(5-halo-1,3-thiazol-2-yl) benzamide derivatives, such as e.g. the 2-hydroxy-N-(5-chloro-1,3-thiazol-2-yl)benzamide (RM-4848), a method for preparing a tizoxanide amine salt from its prodrug nitazoxanide (NTZ), pharmaceutical compositions comprising tizoxanide amine salts, tizoxanide amine salts for use as an antiviral or antiparasitic agent.
Method for producing triarylorganoborates
The invention relates to a process for preparing triaryl organoborates proceeding from organoboronic esters in the presence of an n-valent cation 1/n K.sup.n+, comprising the anhydrous workup of the reaction mixture and the use of the triaryl organoborates obtained as co-initiator in photopolymer formulations, holographic media and holograms.