A process for manufacturing epoxy monomers and/or epoxides in high yields and useful quality and chemical stability by dehydrochlorination of the corresponding chlorohydrins with an alkaline agent, producing the corresponding side product dry salt in a high purity, characterized in that the process comprises the following steps: a. Reaction of the chlorohydrins with the alkaline agent to form corresponding epoxides and the corresponding precipitated chloride salt; b. Dehydration, and optionally completing the reaction, of the reaction mixture of step (a), by use of an azeotropic agent, added to step (b) or generated in situ in step (a), resulting in the producing of a dehydrated reaction mixture; c. Separating the resulting chloride salt by filtration from the dehydrated reaction mixture (b) and d. Isolating the epoxide from the filtered liquid fraction.

Chemical additives for the stimulation of oil wells and their formulations. The invention discloses a micelle-forming surface tension modifying agent, as well as synthesis processes, to be used to modify rock permeability, which supports pressure and temperature under well conditions. The formulation has as an additional advantage, that it is made up, in most of its components, with ingredients derived from natural origin and that it does not present hydrolysis phenomenon at the well working temperature, it is highly compatible with high pressure and it can be recover for a reinjection. The invention can be used in different proportions of formulations for stimulating oil wells.

Chemical additives for the stimulation of oil wells and their formulations. The invention discloses a micelle-forming surface tension modifying agent, as well as synthesis processes, to be used to modify rock permeability, which supports pressure and temperature under well conditions. The formulation has as an additional advantage, that it is made up, in most of its components, with ingredients derived from natural origin and that it does not present hydrolysis phenomenon at the well working temperature, it is highly compatible with high pressure and it can be recover for a reinjection. The invention can be used in different proportions of formulations for stimulating oil wells.

Provided herein are processes for synthesizing Mcl-1 inhibitors and intermediates such as compound Z that can be used to prepare them. In particular, provided herein are processes for synthesizing compound A1, and salts or solvates thereof and compound A2, and salts and solvates thereof. ##STR00001##

Provided herein are processes for synthesizing Mcl-1 inhibitors and intermediates such as compound Z that can be used to prepare them. In particular, provided herein are processes for synthesizing compound A1, and salts or solvates thereof and compound A2, and salts and solvates thereof. ##STR00001##