The invention relates to compounds of formula (I) and related aspects. ##STR00001##

The invention relates to compounds of formula (I) and related aspects. ##STR00001##

Described herein are .sup.9-THC prodrugs, methods of making .sup.9-THC prodrugs, formulations comprising .sup.9-THC prodrugs and methods of using .sup.9-THC. One embodiment described herein relates to the transdermal administration of a .sup.9-THC prodrug for treating and preventing diseases and/or disorders.

Described herein are .sup.9-THC prodrugs, methods of making .sup.9-THC prodrugs, formulations comprising .sup.9-THC prodrugs and methods of using .sup.9-THC. One embodiment described herein relates to the transdermal administration of a .sup.9-THC prodrug for treating and preventing diseases and/or disorders.

Disclosed are substituted tetrahydro-(5H)-chromen-5-one and hexahydro-(5H)-chromen-5-one derivatives of formula (I) possessing woody, peppery notes which is reminiscent of Rotundone. A method of their production and consumer products comprising them is also disclosed.

Disclosed are substituted tetrahydro-(5H)-chromen-5-one and hexahydro-(5H)-chromen-5-one derivatives of formula (I) possessing woody, peppery notes which is reminiscent of Rotundone. A method of their production and consumer products comprising them is also disclosed.

The present invention relates to substituted hexahydro-5H-chromen-5-one and/or substituted tetrahydrobenzofuran-4(2H)-one derivatives which are useful as fragrance or flavor materials.

The present invention relates to substituted hexahydro-5H-chromen-5-one and/or substituted tetrahydrobenzofuran-4(2H)-one derivatives which are useful as fragrance or flavor materials.

Novel compounds and their use for promoting hair growth or inhibiting inflammatory disorders thereof are provided, the compounds have a structure of a formula (I) or a formula (II) or a formula (III), and the compounds or their pharmaceutically acceptable salts can be used for the manufacture of pharmaceutical composition for promoting hair growth or inhibiting inflammatory disorders, the inflammatory disorders including acute respiratory distress syndrome or acute liver injury.

Novel compounds and their use for promoting hair growth or inhibiting inflammatory disorders thereof are provided, the compounds have a structure of a formula (I) or a formula (II) or a formula (III), and the compounds or their pharmaceutically acceptable salts can be used for the manufacture of pharmaceutical composition for promoting hair growth or inhibiting inflammatory disorders, the inflammatory disorders including acute respiratory distress syndrome or acute liver injury.