Patent classifications
C07D403/04
SELECTIVE NR2B ANTAGONISTS
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands of the NR2B receptor and may be useful for the treatment of various disorders of the central nervous system.
##STR00001##
MATERIALS FOR ELECTRONIC DEVICES
The present application relates to a compound which contains an indenocarbazole group, a particular arylamino group and an electron-deficient group bonded to the indenocarbazole group. The compound is suitable for use in electronic devices, in particular in organic electroluminescent devices.
MATERIALS FOR ELECTRONIC DEVICES
The present application relates to a compound which contains an indenocarbazole group, a particular arylamino group and an electron-deficient group bonded to the indenocarbazole group. The compound is suitable for use in electronic devices, in particular in organic electroluminescent devices.
ETHYNYL DERIVATIVES
The present invention relates to compounds that may be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.
ETHYNYL DERIVATIVES
The present invention relates to compounds that may be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like.
The present invention relates to a compound represented by the formula (I) or a salt thereof.
##STR00001##
wherein each symbol is as described in the specification, or a salt thereof.
Tetrazolones as a Carboxylic Acid Bioisosteres
The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to pharmaceutical compositions that include these compounds, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
BICYCLIC COMPOUND
Provided is a bicyclic compound having an acetyl-CoA carboxylase inhibitory action. A compound represented by the formula:
##STR00001##
wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an acetyl-CoA carboxylase inhibitory action, is useful for the prophylaxis or treatment of cancer, inflammatory diseases and the like, and has superior efficacy.
SYNTHESIS OF HETEROCYCLIC COMPOUNDS
Provided herein are intermediates and processes useful for facile synthesis of compounds of formula (I):
##STR00001##
or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Q, P.sup.1 and P.sup.2 are as defined in this disclosure.
SYNTHESIS OF HETEROCYCLIC COMPOUNDS
Provided herein are intermediates and processes useful for facile synthesis of compounds of formula (I):
##STR00001##
or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Q, P.sup.1 and P.sup.2 are as defined in this disclosure.