C07D405/10

Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists

The disclosure relates to compounds of formula I, which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases. ##STR00001##

COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

The present disclosure provides for an organic electroluminescent device (OLED) including an anode; a cathode; and an emissive layer, disposed between the anode and the cathode. The emissive layer includes a phosphorescent dopant, a first host, and a second host, wherein the first host transports holes, the second host transports electrons, and the first host is fully or partially deuterated. Consumer products that include the OLED are also provided.

FBSA-based therapeutic and radioimaging conjugates targeting carbonic anhydrase positive cancers

The present disclosure relates to compositions and methods of carbonic anhydrase IX inhibitors. The present disclosure also relates to targeting conjugates of carbonic anhydrase IX inhibitors. The present disclosure also relates to the use of targeting conjugates of carbonic anhydrase IX inhibitors in methods of treating disease and for imaging of disease.

COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME

Provided is a compound of Formula 1:

##STR00001## wherein: X and Y are independently O, S, or CZ1Z2; Ring A is a benzene or naphthalene ring; A1 to A4 are independently hydrogen, deuterium, a halogen group, a cyano group, a nitro group, a hydroxyl group, or a substituted or unsubstituted: alkyl, cycloalkyl, aryl, or heterocyclic group; R1 to R6, Z1, and Z2 are independently a substituted or unsubstituted: alkyl, aryl, or heterocyclic group; n1 to n3, m, and l are 0 or 1 and n1+n2+n3 is ≥2; a1 and a2 are 1 to 4; a3 is 1 to 3; a4 is 1 to 6; and when a1 to a4 are each 2 or higher, structures in the parenthesis are the same or different, provided that when Ring A is naphthalene, m is 0, and when l is 1, Ring A is a benzene ring,
and an organic light-emitting device comprising the compound.

COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME

Provided is a compound of Formula 1:

##STR00001## wherein: X and Y are independently O, S, or CZ1Z2; Ring A is a benzene or naphthalene ring; A1 to A4 are independently hydrogen, deuterium, a halogen group, a cyano group, a nitro group, a hydroxyl group, or a substituted or unsubstituted: alkyl, cycloalkyl, aryl, or heterocyclic group; R1 to R6, Z1, and Z2 are independently a substituted or unsubstituted: alkyl, aryl, or heterocyclic group; n1 to n3, m, and l are 0 or 1 and n1+n2+n3 is ≥2; a1 and a2 are 1 to 4; a3 is 1 to 3; a4 is 1 to 6; and when a1 to a4 are each 2 or higher, structures in the parenthesis are the same or different, provided that when Ring A is naphthalene, m is 0, and when l is 1, Ring A is a benzene ring,
and an organic light-emitting device comprising the compound.

ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE

An organic electroluminescence device includes two or more emitting units disposed between an anode and a cathode, and an intermediate layer, in which the intermediate layer contains a phenanthroline compound, the laminated emitting unit includes a first emitting layer containing a first host material and a second emitting layer containing a second host material, and a triplet energy T.sub.1(H1) of the first host material and a triplet energy T.sub.1(H2) of the second host material satisfy a relationship of a numerical formula (Numerical Formula 3),


T.sub.1(H1)>T.sub.1(H2)  (Numerical Formula 3).

COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

A compound, a composition for an organic optoelectronic device, an organic optoelectronic device, and a display device, the compound being represented by Chemical Formula 1:

##STR00001##

COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

A compound, a composition for an organic optoelectronic device, an organic optoelectronic device, and a display device, the compound being represented by Chemical Formula 1:

##STR00001##