Patent classifications
C07D405/12
ALKENE-CONTAINING AMIDE COMPOUND AND APPLICATION THEREOF
An alkene-containing amide compound of formula (I) and agriculturally acceptable salts thereof can be used as herbicides.
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ALKENE-CONTAINING AMIDE COMPOUND AND APPLICATION THEREOF
An alkene-containing amide compound of formula (I) and agriculturally acceptable salts thereof can be used as herbicides.
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Methods and compositions for targeting Tregs using CCR8 inhibitors
The present invention provides compounds of Formula (I) which can be used as CCR8 inhibitors, which can be used as treatment or prevention of cancer using CCR8 inhibitors targeted tumor specific T regulatory cells.
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BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS
Provided herein are compounds that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease
BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS
Provided herein are compounds that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease
MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY
The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.
MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY
The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.
2-(substituted benzene matrix) aromatic formate FTO inhibitor, preparation method therefor, and applications thereof
The invention provides 2-(substituted phenylhetero) aromatic formate FTO inhibitors, a preparation method thereof, and applications thereof. Specifically, disclosed in the present invention are a 2-(substituted phenylhetero) aromatic formate compound represented by the following formula (I), and a pharmaceutically acceptable salt, a hydrate or a solvate thereof, which can be used as an FTO targeting inhibitor for treating diseases associated with FTO targets, including obesity, metabolic syndrome (MS), type 2 diabetes (T2D), Alzheimer's diseases, and cancers such as breast cancers, small-cell lung cancers, human bone marrow rhabdomyosarcoma, pancreatic cancer, malignant glioblastoma and the like. ##STR00001##
AHR inhibitors and uses thereof
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
AHR inhibitors and uses thereof
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.