The present invention provides compounds and methods for modulation of the quorum sensing of bacteria. In an embodiment, the compounds of the present invention are able to act as replacements for naturally occurring bacterial quorum sensing ligands in a ligand-protein binding system; that is, they imitate the effect of natural ligands and produce an agonistic effect. In another embodiment, the compounds of the present invention are able to act in a manner which disturbs or inhibits the naturally occurring ligand-protein binding system in quorum sensing bacteria; that is, they produce an antagonistic effect. The compounds of the present invention comprise N-acylated-homoserine lactones (AHLs) comprised of a wide range of acyl groups.

Disclosed herein, inter alia, are trioxolane compounds and methods of using the same for treatment and detection of diseases.

Disclosed herein, inter alia, are trioxolane compounds and methods of using the same for treatment and detection of diseases.

An organic electroluminescence device includes a first electrode, a hole transport region disposed on the first electrode, an emission layer disposed on the hole transport region, an electron transport region disposed on the emission layer, and a second electrode disposed on the electron transport region, wherein the hole transport region includes a polycyclic compound represented by Formula 1, and the device shows high emission efficiency:

##STR00001##

This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.

This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.

An organic electroluminescence device having an improved performance and a compound represented by formula (1), which is a novel material that enables the organic electroluminescence device:

##STR00001## wherein, X, Ar.sup.1 to Ar.sup.5, R.sup.1 to R.sup.20, *a, and *b are the same as those defined in the specification.

An organic electroluminescence device having an improved performance and a compound represented by formula (1), which is a novel material that enables the organic electroluminescence device:

##STR00001## wherein, X, Ar.sup.1 to Ar.sup.5, R.sup.1 to R.sup.20, *a, and *b are the same as those defined in the specification.

An organic compound having a tetraphenyl moiety and at least one fused hetero aryl moiety having at least one oxygen and/or sulfur on a ring and bonded to the tetraphenyl moiety directly or indirectly, and a light emitting diode and a light emitting device having the organic compound are disclosed. The organic compound has excellent thermal resistance property and hole mobility property. The organic compound can be incorporated into a hole transfer layer, an electron blocking layer and/or a charge generation layer of the light emitting diode. Therefore, the light emitting diode and light emitting device according to the present invention have decreased driving voltage and enhanced luminous efficiency.

An organic compound having a tetraphenyl moiety and at least one fused hetero aryl moiety having at least one oxygen and/or sulfur on a ring and bonded to the tetraphenyl moiety directly or indirectly, and a light emitting diode and a light emitting device having the organic compound are disclosed. The organic compound has excellent thermal resistance property and hole mobility property. The organic compound can be incorporated into a hole transfer layer, an electron blocking layer and/or a charge generation layer of the light emitting diode. Therefore, the light emitting diode and light emitting device according to the present invention have decreased driving voltage and enhanced luminous efficiency.