Patent classifications
C07D409/10
Heterocyclic P2Y.SUB.14 .receptor antagonists
Disclosed are compounds of formulas (I)-(IX) for treating or preventing a disease or disorder responsive to antagonism of a P2Y.sub.14R receptor agonist in a mammal in need thereof, wherein R.sup.1-R.sup.8, X, Y, Z, X′, Y′, Z′, and A are as defined herein, that are useful in treating an inflammatory such as asthma, cystic fibrosis, and sterile inflammation of the kidney. ##STR00001##
Heterocyclic P2Y.SUB.14 .receptor antagonists
Disclosed are compounds of formulas (I)-(IX) for treating or preventing a disease or disorder responsive to antagonism of a P2Y.sub.14R receptor agonist in a mammal in need thereof, wherein R.sup.1-R.sup.8, X, Y, Z, X′, Y′, Z′, and A are as defined herein, that are useful in treating an inflammatory such as asthma, cystic fibrosis, and sterile inflammation of the kidney. ##STR00001##
Organic electroluminescent compound and organic electroluminescent device comprising the same
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent device having a low driving voltage and/or a high luminous efficiency and/or a long lifespan can be provided, by comprising an organic electroluminescent compound according to the present disclosure.
Organic electroluminescent compound and organic electroluminescent device comprising the same
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent device having a low driving voltage and/or a high luminous efficiency and/or a long lifespan can be provided, by comprising an organic electroluminescent compound according to the present disclosure.
MASP-2 inhibitors and methods of use
The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
MASP-2 inhibitors and methods of use
The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.
Nitrogen-containing compound, organic electroluminescent device and electronic apparatus
The present disclosure provides a nitrogen-containing compound, an organic electroluminescent device and an electronic apparatus, belonging to the technical field of organic materials. The nitrogen-containing compound of the present disclosure has a carbazole structure and a fluorenyl group, two cooperating with each other and has a high first triplet energy level. Therefore, the nitrogen-containing compound of the present disclosure is suitable for use as a host material of a light-emitting in an organic electroluminescent device. The nitrogen-containing compound can improve the performance of the organic electroluminescent device.
COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE
To provide a compound that further improves the capability of an organic EL device, an organic EL device having a further improved device capability, and an electronic device including the organic EL device. A compound represented by the following formula (1) (wherein *p, *q, *r, *s, *b, *a, R.sup.1, R.sup.2, R.sup.11 to R.sup.18, L, and R.sup.31 to R.sup.35 are defined in the description), an organic electroluminescent device containing the compound, and an electronic device including the organic electroluminescent device.
##STR00001##
COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE
To provide a compound that further improves the capability of an organic EL device, an organic EL device having a further improved device capability, and an electronic device including the organic EL device. A compound represented by the following formula (1) (wherein *p, *q, *r, *s, *b, *a, R.sup.1, R.sup.2, R.sup.11 to R.sup.18, L, and R.sup.31 to R.sup.35 are defined in the description), an organic electroluminescent device containing the compound, and an electronic device including the organic electroluminescent device.
##STR00001##
Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).