Patent classifications
C07D411/12
METHOD FOR THE PREPARATION OF THIOCARBONATES
A process can be used for the preparation of a compound with at least one five-membered cyclic monothiocarbonate group. The process involves a) using a compound with at least one epoxy group as starting material; b) reacting the compound with phosgene or an alkyl chloroformate, thus giving an adduct; and c) reacting the adduct with a compound containing anionic sulfur, thus obtaining the compound with at least one five-membered cyclic monothiocarbonate group.
METHOD FOR THE PREPARATION OF THIOCARBONATES
A process can be used for the preparation of a compound with at least one five-membered cyclic monothiocarbonate group. The process involves a) using a compound with at least one epoxy group as starting material; b) reacting the compound with phosgene or an alkyl chloroformate, thus giving an adduct; and c) reacting the adduct with a compound containing anionic sulfur, thus obtaining the compound with at least one five-membered cyclic monothiocarbonate group.
MICROBIOCIDAL THIAZOLE DERIVATIVES
Compounds of the formula (I), wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.
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Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof
Disclosed are compounds of general formulas I-III that may be used to inhibit the action of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) or dual FAAH/MAGL. ##STR00001##
Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof
Disclosed are compounds of general formulas I-III that may be used to inhibit the action of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL) or dual FAAH/MAGL. ##STR00001##
PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haematopoietic system including the haematologic system in human and veterinary medicine.
PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY
The present invention comprises novel aromatic molecules, which can be used in the treatment of pathological conditions, such as cancer, skin diseases, muscle disorders, and immune system-related disorders such as disorders of the haematopoietic system including the haematologic system in human and veterinary medicine.
Reduction of the odor of monothiocarbonate compounds by addition of oxidants
A process reduces the odor of compounds with al least one five-membered cyclic monothiocarbonate group, referred to as monothiocarbonate compounds. The monothiocarbonate compounds are in are liquid phase and are brought into contact with an oxidant.