Patent classifications
C07D491/16
IMMUNOCONJUGATES AND METHODS
Immunoconjugates of the Formula (I) include a linking group for linking an antibody targeting ligand (Ab) to a drug (D). Embodiments of such immunoconjugates are useful for delivering the drug to selected cells or tissues, e.g., for the treatment of cancer.
Ab-[S-L.sup.1-L.sup.2-L.sup.3-L.sup.4-L.sup.5-L.sup.6-L.sup.7-D].sub.n (I)
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
Provided are metalloorganic and organic compounds comprising a multicyclic system wherein a central nitrogen atom is part of two 5-membered rings which are fused together, and which are further fused together with three 6-membered aromatic rings. Also provided are formulations comprising these compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these compounds and compositions.
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
Provided are metalloorganic and organic compounds comprising a multicyclic system wherein a central nitrogen atom is part of two 5-membered rings which are fused together, and which are further fused together with three 6-membered aromatic rings. Also provided are formulations comprising these compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these compounds and compositions.
HOST MATERIAL, COMPOSITION, AND ORGANIC ELECTROLUMINESCENT ELEMENT
To improve the emission efficiency, the driving voltage and the lifetime of an organic light-emitting device using a delayed fluorescent material. A host material for a delayed fluorescent material, containing a compound represented by the following general formula: R.sup.1 to R.sup.5 each are a substituent not containing a cyano group. n1 to n5 each are 0 to 4, Ar is a monocyclic arylene group or a monocyclic heteroarylene group.
##STR00001##
Materials for organic electroluminescent devices
The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.
Materials for organic electroluminescent devices
The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.
EIF4A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO
The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof.
##STR00001##
For Formula I compounds X, Y, R.sup.1, R.sup.2, R.sup.3a, R.sup.3b, R.sup.4a, R.sup.4b and R.sup.5 are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.
EIF4A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO
The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof.
##STR00001##
For Formula I compounds X, Y, R.sup.1, R.sup.2, R.sup.3a, R.sup.3b, R.sup.4a, R.sup.4b and R.sup.5 are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.
HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME
Provided is a low sublimation temperature heterocyclic compound of Chemical Formula 1:
##STR00001## wherein, in Chemical Formula 1, adjacent one or more pairs of * bond to X.sub.1 and X.sub.2 of the following Chemical Formula 2:
##STR00002##
where * means the part of Chemical Formula 1 bonding to X.sub.1 and X.sub.2, and the substituents are as defined in the specification, and an organic light emitting device including the same, whereby the heterocyclic compound of Chemical Formula 1 increases efficiency and stability of the organic light emitting device.
HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME
Provided is a low sublimation temperature heterocyclic compound of Chemical Formula 1:
##STR00001## wherein, in Chemical Formula 1, adjacent one or more pairs of * bond to X.sub.1 and X.sub.2 of the following Chemical Formula 2:
##STR00002##
where * means the part of Chemical Formula 1 bonding to X.sub.1 and X.sub.2, and the substituents are as defined in the specification, and an organic light emitting device including the same, whereby the heterocyclic compound of Chemical Formula 1 increases efficiency and stability of the organic light emitting device.