Patent classifications
C07D495/06
Ergoline compounds and uses thereof
Provided herein are ergoline compounds and pharmaceutical compositions thereof. In some embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT.sub.1A, 5-HT.sub.1B and 5-HT.sub.1D receptors without agonizing the 5-HT.sub.2B receptor using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the 5-HT.sub.2B adrenergic alpha.sub.2A and/or the alpha.sub.2B receptors using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the D2 and D3 receptor using the compounds and pharmaceutical compositions disclosed herein.
Ergoline compounds and uses thereof
Provided herein are ergoline compounds and pharmaceutical compositions thereof. In some embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT.sub.1A, 5-HT.sub.1B and 5-HT.sub.1D receptors without agonizing the 5-HT.sub.2B receptor using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the 5-HT.sub.2B adrenergic alpha.sub.2A and/or the alpha.sub.2B receptors using the compounds and pharmaceutical compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing the D2 and D3 receptor using the compounds and pharmaceutical compositions disclosed herein.
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
Circulene compounds of Formula I or Formula II, and organic light emitting devices (OLED) that include an organic layer disposed between an anode and a cathode, wherein the organic layer includes a compound of Formula I or Formula II. In addition, the OLED can be incorporated into one or more of a consumer product, for example, an electronic component module, and/or a lighting panel.
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ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
Circulene compounds of Formula I or Formula II, and organic light emitting devices (OLED) that include an organic layer disposed between an anode and a cathode, wherein the organic layer includes a compound of Formula I or Formula II. In addition, the OLED can be incorporated into one or more of a consumer product, for example, an electronic component module, and/or a lighting panel.
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CYANATED BENZOXANTHENE AND BENZOTHIOXANTHENE COMPOUNDS
The present invention relates to cyanated compounds of the formula (I) wherein at least one of the radicals R.sup.2, R.sup.3, R.sup.4 and R.sup.5 is CN, and the remaining radicals are selected from hydrogen, chlorine and bromine; X is O, S, SO or SO.sub.2; m is 0, 1, 2, 3 or 4; R.sup.1 is selected from bromine, chlorine, cyano, NR.sup.aR.sup.b, C.sub.1-C.sub.24-alkyl, C.sub.1-C.sub.24-haloalkyl, C.sub.1-C.sub.24-alkoxy, C.sub.1-C.sub.24-haloalkoxy, C.sub.3-C.sub.24-cycloalkyl, heterocycloalkyl, heteroaryl, C.sub.6-C.sub.24-aryl, C.sub.6-C.sub.24-aryloxy, C.sub.6-C.sub.24-aryl-C.sub.1-C.sub.10-alkylene, etc.; A is a diradical selected from diradicals of the general formulae (A.1), (A.2), (A.3), and (A.4) wherein R.sup.6, (R.sup.7).sub.n, (R.sup.8).sub.o and (R.sup.9).sub.p are as defined in the claims and in the description. The invention further relates to color converters comprising at least one polymer as a matrix material and at least one cyanated compound of formula (I) or mixtures thereof as a fluorescent dye, to the use of the color converters and to lighting devices comprising at least one LED and at least one color converter.
CYANATED BENZOXANTHENE AND BENZOTHIOXANTHENE COMPOUNDS
The present invention relates to cyanated compounds of the formula (I) wherein at least one of the radicals R.sup.2, R.sup.3, R.sup.4 and R.sup.5 is CN, and the remaining radicals are selected from hydrogen, chlorine and bromine; X is O, S, SO or SO.sub.2; m is 0, 1, 2, 3 or 4; R.sup.1 is selected from bromine, chlorine, cyano, NR.sup.aR.sup.b, C.sub.1-C.sub.24-alkyl, C.sub.1-C.sub.24-haloalkyl, C.sub.1-C.sub.24-alkoxy, C.sub.1-C.sub.24-haloalkoxy, C.sub.3-C.sub.24-cycloalkyl, heterocycloalkyl, heteroaryl, C.sub.6-C.sub.24-aryl, C.sub.6-C.sub.24-aryloxy, C.sub.6-C.sub.24-aryl-C.sub.1-C.sub.10-alkylene, etc.; A is a diradical selected from diradicals of the general formulae (A.1), (A.2), (A.3), and (A.4) wherein R.sup.6, (R.sup.7).sub.n, (R.sup.8).sub.o and (R.sup.9).sub.p are as defined in the claims and in the description. The invention further relates to color converters comprising at least one polymer as a matrix material and at least one cyanated compound of formula (I) or mixtures thereof as a fluorescent dye, to the use of the color converters and to lighting devices comprising at least one LED and at least one color converter.
NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICES CONTAINING THEM
The present invention relates to compounds of the general formula (11), to a material for an organic electroluminescence device comprising of least one of these compounds, to an organic electroluminescence device comprising at least one of these compounds, and to the use of a compound according to general formula (11) in an organic electroluminescence device as a host material or an electron transporting material.
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HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES
The present invention relates to compounds of the general formula (I) and to a process for their preparation, to an electronic device comprising at least one of these compounds, to an emitting layer, preferably present in an electronic device, comprising at least one compound of general formula (I) and to the use of a compound according to general formula (I) in an electronic device as a host material and/or charge transporting material.
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HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES
The present invention relates to compounds of the general formula (I) and to a process for their preparation, to an electronic device comprising at least one of these compounds, to an emitting layer, preferably present in an electronic device, comprising at least one compound of general formula (I) and to the use of a compound according to general formula (I) in an electronic device as a host material and/or charge transporting material.
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ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME
The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By using the organic electroluminescent compound of the present disclosure, it is possible to provide an organic electroluminescent device having low driving voltage and/or excellent power efficiency and/or improved driving lifespan.