C07D495/16

Macrocyclic MCL-1 Inhibitors and Methods of Use

The present disclosure provides for compounds of Formula (I)

##STR00001##

wherein A.sup.2, A.sup.3, A.sup.4, A.sup.6, A.sup.7, A.sup.8, A.sup.15, R.sup.A, R.sup.5, R.sup.9, R.sup.10A, R.sup.10B, R.sup.11, R.sup.12, R.sup.13, R.sup.14, R.sup.16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents for the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

2D NON-CARBON NANOMATERIALS AND APPLICATIONS THEREOF
20240083909 · 2024-03-14 ·

The present invention discloses methods for synthesis of 2D non-carbon nanomaterials or 2D complex oxides from materials with complex structure e.g. asphaltenes. It discloses a composition comprising a network of one or more 2D non-carbon nanomaterials having a lattice structure. The lattice structure is selected from an orthorhombic system, monoclinic system, triclinic system. The lattice structure is formed by (ASU)n, where ASU is asymmetric unit and n>=1, where ASU is (TxLyMz) where T is an alkaline metal, L is a chalcogen, O is oxygen, x>=5, y>=2, z>=8. The lattice structure is formed by (ASU)n, where ASU is asymmetric unit and n>=1, where ASU is (TxLyMz H) where T is an alkaline metal, L is a chalcogen, O is oxygen, x>=1, y>=1, z>=5. Examples of the disclosed composition are a network of one or more 2D nanostructures having an asymmetric unit of NaSO.sub.5H or Na.sub.2S.sub.2O.sub.8.

2D NON-CARBON NANOMATERIALS AND APPLICATIONS THEREOF
20240083909 · 2024-03-14 ·

The present invention discloses methods for synthesis of 2D non-carbon nanomaterials or 2D complex oxides from materials with complex structure e.g. asphaltenes. It discloses a composition comprising a network of one or more 2D non-carbon nanomaterials having a lattice structure. The lattice structure is selected from an orthorhombic system, monoclinic system, triclinic system. The lattice structure is formed by (ASU)n, where ASU is asymmetric unit and n>=1, where ASU is (TxLyMz) where T is an alkaline metal, L is a chalcogen, O is oxygen, x>=5, y>=2, z>=8. The lattice structure is formed by (ASU)n, where ASU is asymmetric unit and n>=1, where ASU is (TxLyMz H) where T is an alkaline metal, L is a chalcogen, O is oxygen, x>=1, y>=1, z>=5. Examples of the disclosed composition are a network of one or more 2D nanostructures having an asymmetric unit of NaSO.sub.5H or Na.sub.2S.sub.2O.sub.8.

Organic electroluminescent materials and devices
11917843 · 2024-02-27 · ·

Circulene compounds of Formula I or Formula II, and organic light emitting devices (OLED) that include an organic layer disposed between an anode and a cathode, wherein the organic layer includes a compound of Formula I or Formula II. In addition, the OLED can be incorporated into one or more of a consumer product, for example, an electronic component module, and/or a lighting panel. ##STR00001##

Organic electroluminescent materials and devices
11917843 · 2024-02-27 · ·

Circulene compounds of Formula I or Formula II, and organic light emitting devices (OLED) that include an organic layer disposed between an anode and a cathode, wherein the organic layer includes a compound of Formula I or Formula II. In addition, the OLED can be incorporated into one or more of a consumer product, for example, an electronic component module, and/or a lighting panel. ##STR00001##

ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND LIGHTING SYSTEM, USING SAID ELEMENT
20190355916 · 2019-11-21 ·

An organic electroluminescent element including a substrate, a pair of electrodes including an anode and a cathode, disposed on the substrate, and at least one organic layer including a light emitting layer, disposed between the electrodes, in which at least one kind of compound represented by the following general formula is contained in any layer of the at least one organic layer, is an organic electroluminescent element, in which the generation of dark spots during driving is inhibited:

##STR00001##

ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND LIGHTING SYSTEM, USING SAID ELEMENT
20190355916 · 2019-11-21 ·

An organic electroluminescent element including a substrate, a pair of electrodes including an anode and a cathode, disposed on the substrate, and at least one organic layer including a light emitting layer, disposed between the electrodes, in which at least one kind of compound represented by the following general formula is contained in any layer of the at least one organic layer, is an organic electroluminescent element, in which the generation of dark spots during driving is inhibited:

##STR00001##

INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS
20240114782 · 2024-04-04 ·

The present invention relates to aromatic compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.

INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS
20240114782 · 2024-04-04 ·

The present invention relates to aromatic compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.

CARBAZOLE DERIVATIVES

The present invention relates to carbazole derivatives, especially for use in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.