C07D495/20

LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF

The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.

SPIRO COMPOUND AND MEDICAL USES THEREOF

The present invention relates to a spiro compound and medical uses thereof. Specifically, the present invention relates to a spiro compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the same, and is used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor and is used for treating diseases associated with ACC activity. Each substituent in the general formula (I) is as defined in description.

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SPIRO COMPOUND AND MEDICAL USES THEREOF

The present invention relates to a spiro compound and medical uses thereof. Specifically, the present invention relates to a spiro compound represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing the same, and is used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor and is used for treating diseases associated with ACC activity. Each substituent in the general formula (I) is as defined in description.

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CDK Inhibitors And Their Use As Pharmaceuticals
20230257394 · 2023-08-17 ·

The disclosure is directed to compounds of Formula I

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pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

CDK Inhibitors And Their Use As Pharmaceuticals
20230257394 · 2023-08-17 ·

The disclosure is directed to compounds of Formula I

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pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES

Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES

Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

HETEROCYCLIC COMPOUND FOR USE IN ELECTRONIC DEVICES

The present invention relates to heterocyclic compounds, especially for use in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.

Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof
20220010071 · 2022-01-13 ·

Provided are a polyimide precursor, a polyimide precursor solution, a polyimide film, a method for preparing the same, and a use thereof. According to an exemplary embodiment of the present invention, a polyimide film having excellent thermal resistance and satisfying transparency and a low coefficient of linear thermal expansion may be provided, and thus, may be usefully applied in a flexible display field requiring high dimensional stability and the like.

Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof
20220010071 · 2022-01-13 ·

Provided are a polyimide precursor, a polyimide precursor solution, a polyimide film, a method for preparing the same, and a use thereof. According to an exemplary embodiment of the present invention, a polyimide film having excellent thermal resistance and satisfying transparency and a low coefficient of linear thermal expansion may be provided, and thus, may be usefully applied in a flexible display field requiring high dimensional stability and the like.