A novel compound having excellent light emission and heat stability is disclosed. Also disclosed is an organic electroluminescent device having properties such as light emitting efficiency, an operation voltage, and a service life improved by including the compound in at least one organic layer of the device.

A novel compound having excellent light emission and heat stability is disclosed. Also disclosed is an organic electroluminescent device having properties such as light emitting efficiency, an operation voltage, and a service life improved by including the compound in at least one organic layer of the device.

The present invention relates to compounds of Formula I

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or pharmaceutically acceptable salts or solvates thereof. The invention further relates to the use of the compounds of Formula I as A2A inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer. The invention also relates to a process for manufacturing compounds of Formula I.

The present invention relates to new 5,6,7,8-tetrahydropyrido[4,3:4,5]thieno[2,3d] pyrimidin-4(3H)-one derivatives as sigma ligands having a great affinity for sigma receptors, especially sigma-1 (?.sub.1), as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.

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Provided are an organic transistor with high carrier mobility having a semiconductor active layer containing a compound which is represented by the following formula and has a molecular weight of equal to or less than 3,000, a compound, an organic semiconductor material for a non-light-emitting organic semiconductor device, a material for an organic transistor, a coating solution for a non-light-emitting organic semiconductor device, a method for manufacturing an organic transistor, a method for manufacturing an organic semiconductor film, an organic semiconductor film for a non-light-emitting organic semiconductor device, and a method for manufacturing an organic semiconductor material. ##STR00001## (X represents an oxygen, sulfur, selenium, or tellurium atom or NR.sup.5; Y and Z each represents CR.sup.6, an oxygen, sulfur, selenium, or nitrogen atom, or NR.sup.7; a ring containing Y and Z is an aromatic heterocycle; any one of R.sup.1 and R.sup.2 and the aromatic heterocycle containing Y and Z or any one of R.sup.3 and R.sup.4 and a benzene ring may be bonded to each other through a specific divalent linking group; R.sup.1, R.sup.2, and R.sup.5 to R.sup.8 each represent a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or a heteroaryl group; R.sup.3 and R.sup.4 each represent an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or heteroaryl group; and each of m and n is an integer of 0 to 2).

Provided are an organic transistor with high carrier mobility having a semiconductor active layer containing a compound which is represented by the following formula and has a molecular weight of equal to or less than 3,000, a compound, an organic semiconductor material for a non-light-emitting organic semiconductor device, a material for an organic transistor, a coating solution for a non-light-emitting organic semiconductor device, a method for manufacturing an organic transistor, a method for manufacturing an organic semiconductor film, an organic semiconductor film for a non-light-emitting organic semiconductor device, and a method for manufacturing an organic semiconductor material. ##STR00001## (X represents an oxygen, sulfur, selenium, or tellurium atom or NR.sup.5; Y and Z each represents CR.sup.6, an oxygen, sulfur, selenium, or nitrogen atom, or NR.sup.7; a ring containing Y and Z is an aromatic heterocycle; any one of R.sup.1 and R.sup.2 and the aromatic heterocycle containing Y and Z or any one of R.sup.3 and R.sup.4 and a benzene ring may be bonded to each other through a specific divalent linking group; R.sup.1, R.sup.2, and R.sup.5 to R.sup.8 each represent a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or a heteroaryl group; R.sup.3 and R.sup.4 each represent an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or heteroaryl group; and each of m and n is an integer of 0 to 2).

A hydrochloride salt of inupadenant, pharmaceutical compositions thereof, methods of making pharmaceutical compositions of a hydrochloride salt of inupadenant (e.g., crystalline hydrochloride salt of inupadenant) and methods of using the pharmaceutical compositions in combination with carboplatin and pemetrexed in the treatment of non-small cell lung cancer (NSCLC), including squamous NSCLC and nonsquamous NSCLC.

The present invention includes fused tetraphenylene compounds that may be used as charge transporters, hosts or emitters in OLEDs.

Provided are an organic transistor with high carrier mobility having a semiconductor active layer containing a compound which is represented by the following formula and has a molecular weight of equal to or less than 3,000, a compound, an organic semiconductor material for a non-light-emitting organic semiconductor device, a material for an organic transistor, a coating solution for a non-light-emitting organic semiconductor device, a method for manufacturing an organic transistor, a method for manufacturing an organic semiconductor film, an organic semiconductor film for a non-light-emitting organic semiconductor device, and a method for manufacturing an organic semiconductor material.

##STR00001##

(X represents an oxygen, sulfur, selenium, or tellurium atom or NR.sup.5; Y and Z each represents CR.sup.6, an oxygen, sulfur, selenium, or nitrogen atom, or NR.sup.7; a ring containing Y and Z is an aromatic heterocycle; any one of R.sup.1 and R.sup.2 and the aromatic heterocycle containing Y and Z or any one of R.sup.3 and R.sup.4 and a benzene ring may be bonded to each other through a specific divalent linking group; R.sup.1, R.sup.2, and R.sup.5 to R.sup.8 each represent a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or a heteroaryl group; R.sup.3 and R.sup.4 each represent an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or heteroaryl group; and each of m and n is an integer of 0 to 2.)

An organic electroluminescence device includes a first electrode, a hole transport region on the first electrode, an emission layer on the hole transport region, the emission layer including a condensed polycyclic compound of three or more six-membered rings, at least two six-membered rings among the six-membered rings including an electron donor moiety and an electron acceptor moiety at facing positions, respectively, the at least two six-membered rings not being immediately adjacent to each other, an electron transport region on the emission layer, and a second electrode on the electron transport region.