Patent classifications
C07D513/06
THIOESTER PRODRUGS OF MACROCYCLES AS INHIBITORS OF HISTONE DEACETYLASES
The present invention provides a novel macrocyclic prodrug compound of general Formula (I), a pharmaceutical composition comprising a compound of Formula (I), and a method for treating diseases mediated by HDAC enzymes by administering a compound of Formula (I), wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11, A and Z are defined herein.
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CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME
An organic light-emitting device includes a condensed cyclic compound represented by Formula 1:
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The condensed cyclic compound has an electron withdrawing group (EWG) substituent and an electron donating group (EDG) substituent at suitable positions, and thus has a low ΔE.sub.ST and may be used as an effective thermally activated delayed fluorescence (TADF) light-emitting material.
PROCESS FOR THE PREPARATION OF CYCLIC DEPSIPEPTIDES
Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R.sub.1-R.sub.7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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PROCESS FOR THE PREPARATION OF CYCLIC DEPSIPEPTIDES
Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R.sub.1-R.sub.7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.
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BACE1 inhibitors for the treatment of Alzheimer's disease
Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
BACE1 inhibitors for the treatment of Alzheimer's disease
Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES
Abstract: The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic device.
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MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES
Abstract: The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic device.
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MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES
The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.
MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES
The present invention relates to compounds suitable for use in electronic devices, and to electronic devices, especially organic electroluminescent devices, comprising these compounds.