C07F5/05

NOVEL HIGH VOLTAGE 10, 11, AND 12-VERTEX CARBORANE AND BORANE ELECTROLYTES, THEIR USE IN RECHARGABLE BATTERIES, AND PROCESSES FOR THEIR PREPARATION
20200313242 · 2020-10-01 ·

The present disclosure provides electrolytes for an electrochemical device. In some embodiments, these electrolytes are Mg salts comprising 10-vertex or 12-vertex carborane anions. The present disclosure also provides processes for preparing electrolytes for an electrochemical device. In some embodiments, the process comprises reduction of a reactive cation complexed with a 10-vertex or 12-vertex carborane or 12-vertex borate anion to form metal carborane or borate electrolytes. In some embodiments, the process comprises comproportionating a Mg.sup.+2 10-vertex or 12-vertex carborane salt to form a Mg.sup.+1 electrolyte comprising a 10-vertex or 12-vertex carborane. The present disclosure further provides electrochemical devices comprising the electrolytes disclosed herein. In some embodiments, the electrochemical device comprises an electrolyte that is stable at an electrical potential greater than 4 V vs Mg.sup.0/+2. Also provided herein are heterocyctes bearing the 10, 11, and 12 vertex carborane anions for application as catalyst and battery electrolyte components. The methods of making are also disclosed.

Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
20200283456 · 2020-09-10 ·

Borylated Amino Acid (BAA) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.

Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
20200283456 · 2020-09-10 ·

Borylated Amino Acid (BAA) compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.

Boron-containing compounds, compositions, and methods for the deposition of a boron containing films
10763103 · 2020-09-01 · ·

Described herein are boron-containing precursor compounds, and compositions and methods comprising same, for forming boron-containing films. In one aspect, the film is deposited from at least one precursor having the following Formula I or II described herein. ##STR00001##

Boron-containing compounds, compositions, and methods for the deposition of a boron containing films
10763103 · 2020-09-01 · ·

Described herein are boron-containing precursor compounds, and compositions and methods comprising same, for forming boron-containing films. In one aspect, the film is deposited from at least one precursor having the following Formula I or II described herein. ##STR00001##

MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION

A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor housing, an analyte indicator covering at least a portion of the sensor housing, and one or more compounds containing boronate or boronic acid moieties that reduce degradation of the analyte indicator.

BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
20200207789 · 2020-07-02 ·

Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.

BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
20200207789 · 2020-07-02 ·

Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.

Catalyst, Method for Forming Amide Bond, and Method for Producing Amide Compound

A catalyst represented by General Formula (1) below:

##STR00001## where in the General Formula (1), R.sup.1 to R.sup.14 each independently represent a hydrogen atom or a substituent.

PROTEASOME INHIBITORS
20200190118 · 2020-06-18 ·

The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.