C07F9/025

Synthesis Process of X-IPM, Stable Crystal Form and Application Thereof

The present application relates to a new method for synthesizing isophosphoramide nitrogen mustard (X-IPM) that is suitable for industrialized production, involves fewer types of solvents, and leads to stable products with high yield. This method is charazterized mainly by the batchwise addition of M (e.g., M is R.sub.3N with R being ethyl; i.e., M is triethylamine) and the specific post-reaction treatment, which make it possible for the reaction to fully proceed, lead to products with less impurities, high yield and relatively stable properties, and can lead to stable crystallized substances with specific crystal structures. The present application also relates to stable crystal forms of the isophosphoramide nitrogen mustard (X-IPM) prepared by the aforementioned method, and use of the same as reactants for the synthesis of aziridine structure-containing compounds.

ALUMINUM DIETHYLPHOSPHINATE CRYSTAL WITH LOW FINE POWDER CONTENT, PREPARATION METHOD THEREFOR AND USE THEREOF
20250026771 · 2025-01-23 ·

Disclosed are an aluminum diethylphosphinate crystal with a low fine powder content, a preparation method therefor and use thereof in flame retardance of glass fiber-reinforced engineering plastics. In the present invention, a phosphorus-containing aluminum salt complex is used as a seed crystal and is added in a crystallization process of preparing aluminum diethylphosphinate, such that the crystallization process can be effectively regulated and controlled, aluminum diethylphosphinate crystal particles with a low fine powder content, narrow distribution and a large particle size can be obtained, and the problems that the existing aluminum diethylphosphinate powder is prone to bridging, unsmooth feeding and the like can be solved. The present application is applicable to a processing technology of halogen-free flame retardant glass fiber-reinforced engineering plastics. The prepared aluminum diethylphosphinate includes a small amount of phosphorus-containing aluminum salt complex seed crystals, and the flame retardant property of the aluminum diethylphosphinate is not affected.

Process for reducing the chlorine content of organomonophosphites using two solutions

Process with universal usefulness for reducing the chlorine content of organomonophosphites, using two solutions.

Method for reducing the chlorine content of organomonophosphites using dimethylaminobutane, triethylamine or triethanolamine

The invention relates to a universally applicable method for reducing the chlorine content of organomonophosphites using dimethylaminobutane or triethylamine.

Process for reducing the chlorine content of organotetraphosphites

Universally usable process for reducing the chlorine content of organotetraphosphites.

PROCESS FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING TWO SOLUTIONS
20170121355 · 2017-05-04 · ·

Process with universal usefulness for reducing the chlorine content of organomonophosphites, using two solutions.

METHOD FOR REDUCING THE CHLORINE CONTENT OF ORGANOMONOPHOSPHITES USING DIMETHYLAMINOBUTANE, TRIETHYLAMINE OR TRIETHANOLAMINE
20170088570 · 2017-03-30 · ·

The invention relates to a universally applicable method for reducing the chlorine content of organomonophosphites using dimethylaminobutane or triethylamine.

PROCESS FOR REDUCING THE CHLORINE CONTENT OF ORGANOTETRAPHOSPHITES
20170088569 · 2017-03-30 · ·

Universally usable process for reducing the chlorine content of organotetraphosphites.

Substituted 4-Phenyl Pyridines

Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK.sub.1) receptor. The compounds have the general formula (I):

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Hydrochloric acid stripping process for ionic liquid regeneration process

A method for regenerating deactivated acidic ionic liquid is described. The method involves reducing a level of free hydrochloric acid in the deactivated acidic ionic liquid in a removal zone using at least one of heat, a stripping fluid, reduced pressure, and liquid-liquid extraction to form a deactivated acidic ionic liquid having a reduced level of free hydrochloric acid; and regenerating the deactivated acidic ionic liquid having the reduced level of free hydrochloric acid.