This invention provides a method of preparing a β-hematin crystal comprising a step of heating, the β-hematin crystal obtained by such method, and a vaccine adjuvant composition containing the β-hematin crystal. The β-hematin crystal has a needle-like morphology, it has an average particle size of 0.6 to 1.2 μm, and it exhibits main peaks characteristics for angles of diffraction (2θ) of 7.4°, 12.2°, 21.6°, and 24.1° in an X-ray diffraction pattern obtained by powder X-ray diffractometry with Cu—Kα rays (with each peak including a plus-minus 0.2° diffraction angle).

A method of preparing a Metal Organic Framework (MOF) with an acoustically-driven microfluidic platform, the method comprising: depositing a liquid comprising MOF precursors on a piezoelectric substrate of an acoustic microfluidic platform, the MOF precursors comprising a metal ion and an organic ligand, applying acoustic irradiation to the liquid to induce azimuthal liquid recirculation, which causes formation of the MOF within the liquid, and isolating the MOF.

A method for preparing a biogenic guanidine complex, the method including: mixing dimethyl sulfoxide (DMSO) with water in a volume ratio thereof of 1:1 to yield a solvent DMSO-H.sub.2O; adding organic guanidine (G) and a compound MX.sub.2 in a molar ratio G/MX.sub.2=1:1 or 2:1 to the solvent DMSO-H.sub.2O, where the organic guanidine (G) is selected from arginine (Arg), guanidinoacetic acid (Gaa), creatine (Cra), creatinine (Cran), guanine (Gua), and agmatine (Agm); M represents Fe.sup.2+, Mg.sup.2+, or Zn.sup.2+; and X represents Cl.sup.−, CH.sub.3COO.sup.−, or CH.sub.3CH(OH)COO.sup.−; stirring the solvent DMSO-H.sub.2O containing the organic guanidine and the compound MX.sub.2; recycling the solvent DMSO-H.sub.2O through vacuum distillation and obtaining a solid; transferring the solid to a Buchner funnel, and washing the solid with deionized water and ethanol consecutively; and removing the deionized water and ethanol through vacuum filtration, and drying the solid.

The present invention relates to a method for the production of an absorbent made of metal-organic framework structures (MOF), in the case of which at least one metal salt is converted with at least one organic ligand. The conversion is effected at a temperature greater than 100° C. in a solvent mixture which comprises DMSO and water. The invention relates in addition to an adsorbent produced with the method according to the invention or to a substrate coated with such an adsorbent and also to possibilities of use of such an adsorbent or substrate.

The present invention to provide a highly proton conducting metal organic material constituting of phosphate ester based ligand immobilized via gelation with Fe.sup.3+ ion in DMF which is used as conducting electrolyte in PEFMCs.

The invention relates to an improved process for preparing metal-organic framework materials, metal-organic frameworks obtainable by such processes, methods using the same, and the use thereof. The process of the invention provides an improved process for preparing metal-organic frameworks in particular monocrystalline metal-organic frameworks having large crystal sizes. The invention also relates to metal organic frameworks comprising iron or titanium, and their uses.

In one aspect, the present disclosure relates to a Magnetic Resonance Imaging (MRI) and Spectroscopic Imaging (MRSI) agent wherein the agent comprises a polyazamacrocyclic ligand coordinated to a first row transition metal ion. In another aspect, the disclosure relates to a method of using the MRI/MRSI agents of the present disclosure to monitor tissue temperature and/or pH in a patient in need thereof. In another aspect, the disclosure relates to a method of using the MRI/MRSI agents of the present disclosure to monitor the efficacy of a cancer treatment in a patient in need thereof.

A method for producing metal carbonate is disclosed. The method includes the following steps of providing a first mixture of metal and a catalyst containing iron, NO groups, and N-containing ligands first; then introducing carbon dioxide to the first mixture to form a second mixture and obtaining a product. The method described here can improve the yield and decrease the cost of metal carbonate production.

Described herein are corrole-based frameworks and methods for making the same. The corrole-based frameworks have unique structural and physical properties, which lends them to be versatile in a number of different applications and uses such as in gas storage/separation, proton conduction, biomedicine, sensing, and catalysis. In one aspect, the corrole-based frameworks are organic frameworks. In other aspects, the corrole-based frameworks are metal-organic frameworks.

A transition metal amino borohydride material includes a first row transition metal in conjunction with an amine ligand and borohydride, in a condition of having been thermally treated to a temperature of at least 70° C. and up to but not including 800° C. An exemplary such material, Fe(DETA)(BH.sub.4).sub.2 having been heat treated at 300° C., had good hydrogen storage characteristics.