A sulfinate glycosyl donor of formula I and a method for preparing same as well as use thereof in preparing a glycoside compound including a thioglycoside compound and a carbon glycoside compound are provided. The sulfinate glycosyl donor has a special sulfinate structure. When the sulfinate glycosyl donor is used as a raw material to prepare the glycoside compound, an additional initiator does not need to be added, such that the production cost is saved, the generation of byproducts is reduced, and the glycoside compound with a purity greater than 98% is obtained. The sulfinate glycosyl donor can be used in the preparation of the glycoside compound such as the thioglycoside compound and the carbon glycoside compound.

A sulfinate glycosyl donor of formula I and a method for preparing same as well as use thereof in preparing a glycoside compound including a thioglycoside compound and a carbon glycoside compound are provided. The sulfinate glycosyl donor has a special sulfinate structure. When the sulfinate glycosyl donor is used as a raw material to prepare the glycoside compound, an additional initiator does not need to be added, such that the production cost is saved, the generation of byproducts is reduced, and the glycoside compound with a purity greater than 98% is obtained. The sulfinate glycosyl donor can be used in the preparation of the glycoside compound such as the thioglycoside compound and the carbon glycoside compound.

An acid diffusion control agent includes a compound represented by a formula (1), a compound represented by a formula (2) or both thereof. R.sup.1 represents a hydrocarbon group comprising a monovalent alicyclic structure, or the like. R.sup.2 and R.sup.3 each independently represent a monovalent hydrocarbon group, or the like. R.sup.4 and R.sup.5 each independently represent a monovalent hydrocarbon group, or the like. R.sup.6 and R.sup.7 each independently represent a monovalent hydrocarbon group, or the like. R.sup.8 represents a monocyclic heterocyclic group together with the ester group and with the carbon atom. n is an integer of 1 to 6. R.sup.9 represents a monovalent hydrocarbon group, or the like. R.sup.10 represents a monovalent hydrocarbon group having 1 to 10 carbon atoms. R.sup.11 and R.sup.12 each independently represent a monovalent hydrocarbon group, or the like. R.sup.13 and R.sup.14 each independently represent a monovalent hydrocarbon group, or the like.

##STR00001##

An acid diffusion control agent includes a compound represented by a formula (1), a compound represented by a formula (2) or both thereof. R.sup.1 represents a hydrocarbon group comprising a monovalent alicyclic structure, or the like. R.sup.2 and R.sup.3 each independently represent a monovalent hydrocarbon group, or the like. R.sup.4 and R.sup.5 each independently represent a monovalent hydrocarbon group, or the like. R.sup.6 and R.sup.7 each independently represent a monovalent hydrocarbon group, or the like. R.sup.8 represents a monocyclic heterocyclic group together with the ester group and with the carbon atom. n is an integer of 1 to 6. R.sup.9 represents a monovalent hydrocarbon group, or the like. R.sup.10 represents a monovalent hydrocarbon group having 1 to 10 carbon atoms. R.sup.11 and R.sup.12 each independently represent a monovalent hydrocarbon group, or the like. R.sup.13 and R.sup.14 each independently represent a monovalent hydrocarbon group, or the like. ##STR00001##

An acid diffusion control agent includes a compound represented by a formula (1), a compound represented by a formula (2) or both thereof. R.sup.1 represents a hydrocarbon group comprising a monovalent alicyclic structure, or the like. R.sup.2 and R.sup.3 each independently represent a monovalent hydrocarbon group, or the like. R.sup.4 and R.sup.5 each independently represent a monovalent hydrocarbon group, or the like. R.sup.6 and R.sup.7 each independently represent a monovalent hydrocarbon group, or the like. R.sup.8 represents a monocyclic heterocyclic group together with the ester group and with the carbon atom. n is an integer of 1 to 6. R.sup.9 represents a monovalent hydrocarbon group, or the like. R.sup.10 represents a monovalent hydrocarbon group having 1 to 10 carbon atoms. R.sup.11 and R.sup.12 each independently represent a monovalent hydrocarbon group, or the like. R.sup.13 and R.sup.14 each independently represent a monovalent hydrocarbon group, or the like. ##STR00001##

Provided are methods for the efficient stereoselective formation of glycosidic bonds, without recourse to prosthetic or directing groups.

Provided are methods for the efficient stereoselective formation of glycosidic bonds, without recourse to prosthetic or directing groups.

Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.

Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.

The present invention pertains to a process for producing three-dimensional, self-supporting and/or substrate-supported formed pieces or structures on surfaces by means of site-selective solidification of a liquid to pasty, organic or organically modified material within a bath consisting of this material by means of two- or multiphoton polymerization, whereby the material has at least one compound that has both an organic radical polymerizable via two-photon or multiphoton polymerization and a biocompatible, biodegradable or bioresorbable group, and/or wherein the bath material additionally contains groups or radicals, which are available for an inorganic crosslinking or which are already inorganically crosslinked, providing that both an organic radical polymerizable via two-photon or multiphoton polymerization and a biocompatible, biodegradable or bioresorbable group must be contained in the material. The formed pieces or surface structures according to the present invention are suitable as matrices for binding live cells, which can be multiplied after that or stimulated for the production of specific substances. They can be used, e.g., as an extracorporeal matrix or as an implant.