The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.

The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.

A compound inhibiting a sodium-glucose cotransporter 1, and a pharmaceutically acceptable salt and a stereoisomer thereof. The compound is used in a pharmaceutical composition. Also disclosed are methods for preparing and using the pharmaceutical composition, and an application in preparing a drug and a composition of the compound for treating and improving diabetes, cardio-vascular diseases, weight reduction, fatty liver, astriction, and metabolism-related diseases, and cancer therapy.

A compound inhibiting a sodium-glucose cotransporter 1, and a pharmaceutically acceptable salt and a stereoisomer thereof. The compound is used in a pharmaceutical composition. Also disclosed are methods for preparing and using the pharmaceutical composition, and an application in preparing a drug and a composition of the compound for treating and improving diabetes, cardio-vascular diseases, weight reduction, fatty liver, astriction, and metabolism-related diseases, and cancer therapy.

Provided are a compound that inhibits sodium-glucose co-transporter 1, and a pharmaceutically acceptable salt and stereoisomer thereof. The compound is used in a pharmaceutical composition and preparation and usage methods, which comprise an application of a drug and composition thereof in the preparation for treating and improving diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver disease, constipation, metabolism-related diseases and tumor treatment.

Provided are a compound that inhibits sodium-glucose co-transporter 1, and a pharmaceutically acceptable salt and stereoisomer thereof. The compound is used in a pharmaceutical composition and preparation and usage methods, which comprise an application of a drug and composition thereof in the preparation for treating and improving diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver disease, constipation, metabolism-related diseases and tumor treatment.

Provided in the present invention are a compound for inhibiting sodium glucose cotransporter 1, and a pharmaceutically acceptable salt and a stereoisomer of the compound. The compound is used for a pharmaceutical composition, and further provided is a method for preparing and using same, comprising the use of the drug or the composition in the preparation for the treatment and improvement of diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver, constipation, metabolism-related diseases and in the treatment of tumors.

Provided in the present invention are a compound for inhibiting sodium glucose cotransporter 1, and a pharmaceutically acceptable salt and a stereoisomer of the compound. The compound is used for a pharmaceutical composition, and further provided is a method for preparing and using same, comprising the use of the drug or the composition in the preparation for the treatment and improvement of diabetes, cardiovascular and cerebrovascular diseases, weight loss, fatty liver, constipation, metabolism-related diseases and in the treatment of tumors.

The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.

A class of compounds as a SGLT1/SGLT2/DPP4 triple inhibitor, and an application in preparation of a drug serving as the SGLT1/SGLT2/DPP4 triple inhibitor. Compounds represented by formula (I), and isomers and pharmaceutically-acceptable salts thereof are specifically involved.

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