Patent classifications
C07K14/205
COMPOSITION FOR INHIBITING GROWTH OF BACTERIUM HAVING MENAQUINONE SYNTHESIS PATHWAY THROUGH FUTALOSINE OR FUTALOSINE DERIVATIVE
The present invention provides a composition for inhibiting proliferation of a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative, which contains a fatty acid having 18 carbon atoms and a hydroxyl group at the 10-position as an active ingredient. Furthermore, the present invention provides a composition for preventing or treating a disease caused by a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative.
COMPOSITION FOR INHIBITING GROWTH OF BACTERIUM HAVING MENAQUINONE SYNTHESIS PATHWAY THROUGH FUTALOSINE OR FUTALOSINE DERIVATIVE
The present invention provides a composition for inhibiting proliferation of a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative, which contains a fatty acid having 18 carbon atoms and a hydroxyl group at the 10-position as an active ingredient. Furthermore, the present invention provides a composition for preventing or treating a disease caused by a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative.
CRISPR/CAS FUSION PROTEINS AND SYSTEMS
Engineered Cas9 systems are disclosed herein.
CRISPR/CAS FUSION PROTEINS AND SYSTEMS
Engineered Cas9 systems are disclosed herein.
ANTIGENIC EPSTEIN BARR VIRUS POLYPEPTIDES
This disclosure relates to antigenic EBV polypeptides and their use in eliciting antibodies against EBV. Also disclosed are antigenic polypeptides comprising an EBV polypeptide and a ferritin protein.
QUANTIFICATION OF BIOCONJUGATE GLYCOSYLATION
The present invention provides analytical tools for the characterisation of bioconjugates, in particular for the measurement of glycosylation levels, and methods for absolute quantification of glycosylation sequences, as well as sequences and glycosylation sites for use in such methods.
QUANTIFICATION OF BIOCONJUGATE GLYCOSYLATION
The present invention provides analytical tools for the characterisation of bioconjugates, in particular for the measurement of glycosylation levels, and methods for absolute quantification of glycosylation sequences, as well as sequences and glycosylation sites for use in such methods.
Peptides and their use in diagnosis
There is provided novel peptides for use in diagnosis of CagA+ H. pylori infection or the prediction of risk for gastric cancer. The peptides bind antibodies from CagA+ H. pylori patients with high specificity and sensitivity, and can be used for example in a diagnostic kit.
Peptides and their use in diagnosis
There is provided novel peptides for use in diagnosis of CagA+ H. pylori infection or the prediction of risk for gastric cancer. The peptides bind antibodies from CagA+ H. pylori patients with high specificity and sensitivity, and can be used for example in a diagnostic kit.
CONSTRUCTION AND USE OF TANDEM EPITOPE POLYPEPTIDE OF OUTER MEMBRANE PROTEIN OF CAMPYLOBACTER JEJUNI, GENE, RECOMBINANT PLASMID AND RECOMBINANT BACTERIA
The disclosure provides the construction and use of tandem epitope polypeptide of outer membrane protein of campylobacter jejuni, gene, recombinant, plasmid recombinant bacteria, belonging to the technical field of genetic engineering vaccines. The tandem epitope polypeptide of outer membrane protein of campylobacter jejuni can activate the immune response of mice, and has the effect of efficiently preventing Campylobacter jejuni colonization. The tandem epitope polypeptide of the disclosure can be used for preparing vaccines for preventing campylobacter jejuni infection.