Bivalent epidermal growth factor (EGF) fusion toxin including two EGF domains are provided. The described fusion toxin demonstrates increased binding and cytotoxicity when compared to a fusion toxin having a single EGF binding domain (monovalent). Methods for treating epidermal growth factor receptor (EGFR)-positive cancers and related materials are also provided.

The present invention is directed towards conjugates comprising fragments of the capsular polysaccharide of Type III Group B Streptococcus (GBS). Suitable fragments may be produced synthetically or by depolymerisation of native polysaccharide.

The present invention is directed towards conjugates comprising fragments of the capsular polysaccharide of Type III Group B Streptococcus (GBS). Suitable fragments may be produced synthetically or by depolymerisation of native polysaccharide.

Methods for using the human interleukin-4 receptor (IL-4) as a biomarker for determining patent populations for treatment, predicting disease treatment efficacy, and predicting disease treatment prognosis in a variety of cancers, in particular glioblastoma and recurrent glioblastoma.

The present application relates to microorganisms with enhanced L-branched-chain amino acid productivity comprising a novel polynucleotide and a method for producing L-branched-chain amino acids using the same.

The present application relates to microorganisms with enhanced L-branched-chain amino acid productivity comprising a novel polynucleotide and a method for producing L-branched-chain amino acids using the same.

The present invention relates to the production of bacteriocins, and in particular the production of bacteriocins of class I or II by recombinant expression in coryneform bacteria as the bacterial cell host. Also provided are modified coryneform bacteria for use as production hosts for production of bacteriocins.

The present invention relates to the production of bacteriocins, and in particular the production of bacteriocins of class I or II by recombinant expression in coryneform bacteria as the bacterial cell host. Also provided are modified coryneform bacteria for use as production hosts for production of bacteriocins.

The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.

The present disclosure relates generally to methods of preparing glycoconjugates containing a saccharide conjugated to a carrier protein by use of stable nitroxyl radical related agent/oxidant as an oxidizing agent, to immunogenic compositions comprising such glycoconjugates, and to methods for the use of such glycoconjugates and immunogenic compositions.