Described herein are CB5 polypeptides for the biosynthesis of oxygenated hydrocarbons in modified host cells.

Described herein are CB5 polypeptides for the biosynthesis of oxygenated hydrocarbons in modified host cells.

Provided are a microorganism for producing L-amino acid, having increased cytochrome C activity, and an L-amino acid production method using the microorganism.

The present disclosure provides a recombinant adeno-associated vector comprising a codon-optimized sequence encoding CYP4V2 linked to selected gene expression regulatory sequences and its use in treating Bietti Crystalline Dystrophy (BCD).

The present disclosure provides a recombinant adeno-associated vector comprising a codon-optimized sequence encoding CYP4V2 linked to selected gene expression regulatory sequences and its use in treating Bietti Crystalline Dystrophy (BCD).

The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.

The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.

The present invention provides improved P450-BM3 variants with improved activity. In some embodiments. the P450-BM3 variants exhibit improved activity over a wide range of substrates.

The present invention provides improved P450-BM3 variants with improved activity. In some embodiments. the P450-BM3 variants exhibit improved activity over a wide range of substrates.

Provided herein are methods for treating or preventing diseases of the eye such as Bietti's Crystalline Dystrophy (BCD) using, for example, vectors for delivering a gene encoding a CYP4V2 protein to the retina (for example, to the retinal pigment epithelial (RPE) cells) or using cells comprising such vectors.