C07K16/10

METHOD FOR SELECTING ANTIBODY FRAGMENTS, RECOMBINANT ANTIBODIES PRODUCED THEREFROM, AND USES THEREOF

Disclosed herein are methods for selecting an antibody fragment specific to an influenza virus. According to certain embodiments of the present disclosure, the influenza virus may be influenza virus type A (IAV) or influenza virus type B (IBV). Also disclosed herein are the selected antibodies, recombinant antibody produced from the selected antibodies, and the uses thereof in the diagnosis of influenza virus infection.

CORONAVIRUS DISEASE 2019 (COVID-19) COMBINATION VACCINE
20230210981 · 2023-07-06 ·

Disclosed herein is a vaccine comprising a Coronavirus disease 2019 (COVID-19) antigen in a combination with an immunoglobulin from post-exposure treatment. The antigen can be a consensus antigen. The consensus antigen can be a consensus spike antigen. Also disclosed herein is a method of treating a subject in need thereof, by administering the vaccine to the subject.

Chimeric antigen receptor-modified NK-92 cells

Provided are NK-92 cells expressing a chimeric antigen receptor (CAR). The CAR can comprise an intracellular domain of FcεRIγ. Also described are methods for treating a patient having or suspected of having a disease that is treatable with NK-92 cells, such as cancer or a viral infection, comprising administering to the patient NK-92-CAR cells.

Chimeric antigen receptor-modified NK-92 cells

Provided are NK-92 cells expressing a chimeric antigen receptor (CAR). The CAR can comprise an intracellular domain of FcεRIγ. Also described are methods for treating a patient having or suspected of having a disease that is treatable with NK-92 cells, such as cancer or a viral infection, comprising administering to the patient NK-92-CAR cells.

MULTIPLE RAPID DETECTION KITS AND METHODS FOR VARIOUS VIRUSES
20230212589 · 2023-07-06 ·

Novel Coronavirus/MERS-CoV/Influenza Virus A/B Multiple Rapid Detection Kit is disclosed. The kit has the advantages of high sensitivity, good specificity, high speed (3-15 minutes), simplicity and low cost.

MULTIPLE RAPID DETECTION KITS AND METHODS FOR VARIOUS VIRUSES
20230212589 · 2023-07-06 ·

Novel Coronavirus/MERS-CoV/Influenza Virus A/B Multiple Rapid Detection Kit is disclosed. The kit has the advantages of high sensitivity, good specificity, high speed (3-15 minutes), simplicity and low cost.

Pyrrolobenzodiazepine-anti-CD22 antibody conjugates

The disclosure provides conjugates of an isolated humanized anti-CD22 antibody and PBD dimers.

Immune complex

The present invention relates to immunogenic immune complexes, related compositions, and related methods.

Human zika virus antibodies and methods of use therefor
11692023 · 2023-07-04 · ·

The present disclosure is directed to antibodies binding to and neutralizing Zika virus and methods for use thereof.

Vaccines formed by virus and antigen conjugation

Disclosed herein are methods of forming compounds and exemplary stable compounds in the nature of a conjugated compound at refrigerated or room temperature, which in some embodiments comprises an antigen and virus particle mixed in a conjugation reaction to form a conjugate mixture, such that the conditions and steps of forming these products allow for use of the conjugate mixture as a vaccine, including but not limited to use as a vaccine against various pathogens including for treatment of diseases caused by novel coronaviruses (including SARS-COV 2).