A preparation method for an esterified selenium polysaccharide includes the steps of: adding O═SeCl.sub.2 dropwise to a triethylamine-containing D-galactose allyl glucoside solution and reacting at room temperature to obtain 3,4-oxo-cyclo selenite galactose allyl glucoside; mixing NaHCO.sub.3 into a polysaccharide solution, adding acryloyl chloride dropwise to the polysaccharide solution and maintaining a temperature of a reaction solution to not exceed 40° C. during a dropwise addition to obtain acrylated polysaccharide; and performing a displacement reaction of the acrylated polysaccharide with the 3,4-oxo-cyclo selenite galactose allyl glucoside under an action of a Ru catalyst to obtain the esterified selenium polysaccharide. The esterified selenium polysaccharide prepared by the preparation method improves an immunity of a tested organism by increasing a selenium content in blood.

The present invention relates to a dried, resoluble beta-glucan and methods related to the same. Another aspect of the invention relates to the method of making the resoluble beta-glucan comprising the steps of combining an insoluble beta-glucan with water to form a suspension, followed by the addition of a strong base to form a solution. The solution is then dried to a moisture content of at least 20% by weight or less.

The present invention provides an oligodeoxynucleotide containing humanized K type CpG oligodeoxynucleotide and poly deoxyadenylate, wherein the poly deoxyadenylate is placed on the 3′-side of the humanized K type CpG oligodeoxynucleotide. In addition, the present invention provides a complex containing the aforementioned oligodeoxynucleotide and β-1,3-glucan.

The present invention relates to a process for the purification of complex biocompositions.

The invention provides an improved method of synthesising derivatives of β-D-glucopyranoside-containing polymers, such as chitin, chitosan, cellulose, amylose, pullulan, curdlan, inulin, guar gum or cyclodextrin. The method includes reacting a polymer of formula (III) with a cyclic imide to form a polymer of formula (I) thereby introducing a nitrogen functionality at the 6-position and providing access to 6-deoxy-6-amino-β-D-glucopyranoside-containing polymers. ##STR00001##

The present invention is a multilayered composite comprising porous metal oxide particles that are covalently bonded by way of inorganic ether groups to one or more sites of a first polyhydroxyl-functionalized polymer. This first polymer is in turn covalently bonded by way of inorganic ether groups to one or more sites of a second polyhydroxyl-functionalized polymer. The multilayered composites can be prepared by contacting porous inorganic-oxide particles with a sufficient amount of OH-reactive crosslinking agent to form metal oxide particles imbibed with the crosslinking agent, and then contacting the inorganic-oxide particles with a solution of polyhydroxyl-functionalized polymer under reactive conditions.

Readily water-miscible beta-glucan suspensions and methods of making and using the same. A readily water-miscible beta-glucan suspension includes a beta-glucan and a water-miscible organic fluid that comprises an alcohol, an alpha-hydroxy acid alkyl ester, a polyalkylene glycol alkyl ether, or a combination thereof, wherein the suspension is sufficient such that mixing with water at a shear rate of 40,000 s.sup.−1 or more forms a homogeneous mixture of the suspension and the water. The present invention also provides methods of dispersing the water-miscible beta-glucan suspension in water to form homogenous mixtures of the suspension and the water, methods of treating subterranean formations with such homogeneous mixtures, and methods of making the suspension.

Refined beta-glucans, such as scleroglucan or schizophyllan, and methods of making and using the same, such as for treating subterranean formations. A method of making a refined beta-glucan includes filtering a solution of a crude beta-glucan.

Beta-glucan compositions and methods of making and using the same, such as for treatment of a subterranean formation. A beta-glucan composition includes a beta-glucan and water. Shearing the beta-glucan composition at a shear rate of up to a maximum shear rate of about 300,000 s.sup.−1 or less provides a sheared beta-glucan composition having a viscosity at standard temperature and pressure at 6 rpm of at least about 30 cps and a Filterability Ratio of less or equal to than about 1.5.

A reinforced polymer composite includes a polymer matrix, a strengthening agent, and a dispersing agent. The strengthening agent is a natural fiber having an aspect ratio between 6 and 12 and is included in the composite in amounts up to 30 wt %. The dispersing agent is coconut shell powder having an aspect ratio between 1 and 3 and is included in the composite in amounts up to 10 wt %.