A microbial preparation of Bacillus consisting of: 5%-10% (ww) shrimp and crab shell powders, 85%-90% corn starches, and a RG BV-1 strain in Bacillus velezensis, wherein a base sequence having serial number 1 is presented by 16S rDNA, and the 85%-90% corn starches, the 5%-10% (ww) shrimp and crab shell powders, and the RG BV-1 strain are mixed at a predetermined proportion.

Compositions are provided that contain biologically active components of amniotic fluid including growth factors and other proteins, carbohydrates, lipids, and metabolites. The compositions containing biologically active components of amniotic fluid can be useful for a range of therapeutic treatments including joint and soft tissue repair, regulation of skin condition, and for use in organ preservation, such as for use in organ transplant procedures. Advantages of the compositions include that they can be reproducibly produced, without the inherent variability of amniotic fluid from individual donors, and that they are free of fetal waste.

Compositions are provided that contain biologically active components of amniotic fluid including growth factors and other proteins, carbohydrates, lipids, and metabolites. The compositions containing biologically active components of amniotic fluid can be useful for a range of therapeutic treatments including joint and soft tissue repair, regulation of skin condition, and for use in organ preservation, such as for use in organ transplant procedures. Advantages of the compositions include that they can be reproducibly produced, without the inherent variability of amniotic fluid from individual donors, and that they are free of fetal waste.

Compositions are provided that contain biologically active components of amniotic fluid including growth factors and other proteins, carbohydrates, lipids, and metabolites. The compositions containing biologically active components of amniotic fluid can be useful for a range of therapeutic treatments including joint and soft tissue repair, regulation of skin condition, and for use in organ preservation, such as for use in organ transplant procedures. Advantages of the compositions include that they can be reproducibly produced, without the inherent variability of amniotic fluid from individual donors, and that they are free of fetal waste.

Use of a composition as a barrier to molluscs is disclosed. The composition comprises a combustion product or an alkaline material and is in granular form. The granular composition may be effective and long-acting in such a use due to improved weather resistance compared to loose combustion product or alkaline material. A method of producing such a granular composition comprising a combustion product or an alkaline material and a barrier method preventing access to plants by molluscs with said granular composition comprising a combustion product or an alkaline material are also disclosed. A granular composition comprising at least 98 wt % of a combustion product or an alkaline material, wherein at least 98% of the granules have a size of from 0.5 to 10.0 mm is also disclosed.

Use of a composition as a barrier to molluscs is disclosed. The composition comprises a combustion product or an alkaline material and is in granular form. The granular composition may be effective and long-acting in such a use due to improved weather resistance compared to loose combustion product or alkaline material. A method of producing such a granular composition comprising a combustion product or an alkaline material and a barrier method preventing access to plants by molluscs with said granular composition comprising a combustion product or an alkaline material are also disclosed. A granular composition comprising at least 98 wt % of a combustion product or an alkaline material, wherein at least 98% of the granules have a size of from 0.5 to 10.0 mm is also disclosed.

Disclosed herein are methods for preventing biofilm formation on a surface. The present disclosure also relates to anti-biofilm forming agents, to methods of producing and using them, and to anti-fouling coatings produced therefrom.

Disclosed herein are methods for preventing biofilm formation on a surface. The present disclosure also relates to anti-biofilm forming agents, to methods of producing and using them, and to anti-fouling coatings produced therefrom.

The invention provides combination therapy for use in treating a bacterial biofilm in a subject comprising (a) a polypeptide having serine protease activity and (b) one or more antibiotic compounds. Also provided are compositions and methods of use of the same.

The invention provides combination therapy for use in treating a bacterial biofilm in a subject comprising (a) a polypeptide having serine protease activity and (b) one or more antibiotic compounds. Also provided are compositions and methods of use of the same.