The present invention relates to a core-shell nanoparticle comprising (a) an inorganic core comprising a nanoparticle comprising a metal, a metal oxide or combination thereof, and a silica component; (b) a shell material comprising a copolymer having at least two polymers selected from a pH-responsive polymer and a hydrophobic polymer; and (c) a crosslinker that conjugates the shell material to the inorganic core. There is also provided a method for producing the core-shell nanoparticle and uses thereof.

Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl phenanthroline structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl phenanthroline structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl phenanthroline structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl phenanthroline structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

Provided herein are crosslinked polymers useful in orthodontic appliances and light polymerizable liquid compositions and formulations useful for making crosslinked polymers. Also provided are methods of making an orthodontic appliance comprising a cross-linked polymer formed by a direct fabrication technique.

Provided herein are crosslinked polymers useful in orthodontic appliances and light polymerizable liquid compositions and formulations useful for making crosslinked polymers. Also provided are methods of making an orthodontic appliance comprising a cross-linked polymer formed by a direct fabrication technique.

A gas hydrate hydrogel inhibitor comprising at least one polymer hydrogel particle having from 50 to 100% hydrogel content, the at least one polymer hydrogel particle including an inhibitor selected from the group consisting of: at least one thermodynamic hydrate inhibitor, at least one kinetic hydrate inhibitor, or a combination thereof.

A gas hydrate hydrogel inhibitor comprising at least one polymer hydrogel particle having from 50 to 100% hydrogel content, the at least one polymer hydrogel particle including an inhibitor selected from the group consisting of: at least one thermodynamic hydrate inhibitor, at least one kinetic hydrate inhibitor, or a combination thereof.

Provided herein are crosslinked polymers useful in orthodontic appliances and light polymerizable liquid compositions and formulations useful for making crosslinked polymers. Also provided are methods of making an orthodontic appliance comprising a cross-linked polymer formed by a direct fabrication technique.

Provided herein are crosslinked polymers useful in orthodontic appliances and light polymerizable liquid compositions and formulations useful for making crosslinked polymers. Also provided are methods of making an orthodontic appliance comprising a cross-linked polymer formed by a direct fabrication technique.

The invention is related to a colorant composition used for the color layer in a colored contact lens. The colorant composition improves the adhesion of the colorant to the surface of the contact lens and provides more hydrophilicity and biocompatibility. The colorant composition for the color layer comprises at least one hydrophilic monomer, an adhesive resin, a film-forming agent and a polydopamine-modified colorant.