The invention provides a class of polymeric materials being ABA tri-block or AB di-block, comprised of biodegradable segments and poly(propylene oxide) (PPO) segment and uses thereof.

The invention provides a class of polymeric materials being ABA tri-block or AB di-block, comprised of biodegradable segments and poly(propylene oxide) (PPO) segment and uses thereof.

A polymer film can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The polymer film includes a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

A polyol polymer is obtained from reactants including: a) a non-aromatic epoxy functional compound that includes at least 30 weight % of the total solids weight of the reactants; and b) an aromatic mono-carboxylic acid functional compound, or anhydride thereof, that is substantially free of non-aromatic ethylenic unsaturation. The polyol polymer has ester linkages and hydroxyl functional groups. Further, if the reactants further include an aromatic polycarboxylic acid, the aromatic polycarboxylic acid makes up less than 15 weight % of the total solids weight of the reactants. A coating composition is also prepared with the polyol polymer.

An isopoly-vanadic acid coordination polymer catalyst, method of manufacturing the same, and application thereof are provided. The isopoly-vanadic acid coordination polymer catalyst has a chemical formula of [Co(atrz)(V.sub.2O.sub.6)]. The atrz is a 4-amino-1,2,4-triazole ligand, and [V.sub.2O.sub.6] is a binuclear vanadate anion. The isopoly-vanadic acid coordination polymer catalyst shows strong thermal stability, and it is easy to synthesize with high reproducibility. The isopoly-vanadic acid coordination polymer catalyst has a good catalytic activity towards the bulk ring-opening of p-dioxanone. The resulting poly(p-dioxanone) is stable and uniform. The high molecular weight of the resulting poly(p-dioxanone) has great potential in high polymer materials, in particular the field of medical high polymer materials.

The present invention relates to novel degradable branched-blockcopolymers, comprising a star-shaped copolymer central core or a linear copolymer central core, functionalized with photoreactive groups chosen among aryl-azide, (meth)acrylate or thiol groups. The present invention also relates to the use of these degradable branched-block copolymers as photo-crosslinkers to provide degradable photo-crosslinked elastomers as biomaterials suitable for medical and tissue engineering applications. A method for preparing a degradable photo-crosslinked polymer, preferably a degradable photo-crosslinked elastomer, starting from the branched-block copolymer of the invention via a shaping process and an irradiation step is also provided.

Provided herein are extended release polymers. In one aspect, a composition for sustained release of active ingredients comprises a block polymer having formula: PEG-PCL-PLA-PCL-PEG or PGA-PCL-PEG-PCL-PGA. The extended release block polymers modulate drug release rate based on the hydrophobicity of the PTSgel polymer irrespective of the nature of drug. PTSgel polymers are biodegradable, thermosensitive, and compatible with hydrophilic, hydrophobic, and combinations thereof, biologic or chemical active agents.

Polyester compositions are disclosed herein, as well as methods of making and using such polyesters. In some embodiments, the polyesters are formed from monomers derived from natural oils. In some embodiments, the polyesters are highly branched polymers, such as highly branched polymers that have low viscosity at higher molecular weights.

Polyester compositions are disclosed herein, as well as methods of making and using such polyesters. In some embodiments, the polyesters are formed from monomers derived from natural oils.

Polyester compositions are disclosed herein, as well as methods of making and using such polyesters. In some embodiments, the polyesters are formed from monomers derived from natural oils.