Compounds and compositions are provided which are useful in additive printing, particularly additive printing techniques such as stereolithography (SLA) wherein a macromer is photopolymerized to form a manufactured article. Representative compounds comprise a polyaxial central core (CC) and 2-4 arms of the formula (A)-(B) or (B)-(A) extending from the central core, where at least one of the arms comprise a light-reactive functional group (Q) and (A) is the free-radical polymerization product from monomers selected from trimethylene carbonate (T) and ε-caprolactone (C), while (B) is the free-radical polymerization product from monomers selected from glycolide, lactide and ρ-dioxanone.

Provided herein according to aspects of the present invention are resins that: (a) are suitable for use in additive manufacturing techniques such as bottom-up and top-down stereolithography, (b) produce objects that are bioresorbable, and (c) produce objects that are flexible or elastic (preferably at at least typical room temperatures of 25° C., and in some embodiments at typical human body temperatures of 37° C.). Such resins may include: (a) a bioresorbable polyester oligomer having reactive end groups; (b) non-reactive diluent; (c) optionally reactive diluent; and (d) a photoinitiator.

Provided herein are methods and systems for producing a thermally stable polylactone polymer comprising chain terminating the polymer with an end-capping agent to prevent scission of the polymer. Also provided is a thermally stable polylactone polymer wherein the polymer has a first end and a second end, wherein at least one of said first and second ends terminate in an end-capping agent.

The present disclosure relates to a method and a composition comprising an esterase for enzymatic surface modification of a polyester. The present disclosure also relates to a method of degradation or hydrolysis of an insoluble plant material.

A method of preparing a fluorinated polycaprolactone membrane includes the following steps: (1) reacting a polycaprolactone with an aminoalcohol compound to prepare a hydroxyl-terminated polycaprolactone; (2) reacting the hydroxyl-terminated polycaprolactone with an anhydride to prepare a carboxyl-terminated polycaprolactone; (3) reacting an ethylene glycol bromoisobutyrate with a fluorinated acrylate to prepare a hydroxyl-terminated fluoro-acrylate polymer; (4) reacting the carboxyl-terminated polycaprolactone with the hydroxyl-terminated fluoro-acrylate polymer to prepare a fluorinated polycaprolactone; (5) at room temperature, dissolving the fluorinated polycaprolactone in an organic solvent to prepare a solution; then naturally drying the solution at room temperature to prepare the fluorinated polycaprolactone membrane.

This invention provides the preparation and applications of a degradable dual-component hydrogel. The hydrogel is prepared by mixing component A, component B and solvent; Component A is an o-phthalaldehyde modified degradable polymer; Component B is a water-soluble molecule, a water-soluble synthetic polymer, or a polysaccharide that contains one or more types of the groups selected from primary amine, hydrazine, hydrazide, hydroxylamine and sulfhydryl, with the number of groups not less than 2. This invention achieves the regulation for hydrogel degradability by introducing degradable structures into the polymer skeleton of component A, and obtains hydrogels with rapid degradation. This invention thus solve the dilemma of materials—confronting either the problems of undegradable poly (ethylene glycol) skeleton or the potential risks of the degradable bioproducts introduced—used for preparing the dual-component hydrogel.

The invention features adhesive devices for holding objects (e.g., bone fragments) fixed with respect to each other.

Provided herein according to aspects of the present invention are resins that: (a) are suitable for use in additive manufacturing techniques such as bottom-up and top-down stereolithography, (b) produce objects that are bioresorbable, and (c) produce objects that are flexible or elastic (preferably at at least typical room temperatures of 25° C., and in some embodiments at typical human body temperatures of 37° C.). Such resins may include: (a) a bioresorbable polyester oligomer having reactive end groups; (b) non-reactive diluent; (c) optionally reactive diluent; and (d) a photoinitiator.

Provided is a lactic acid-based block copolymer which is biodegradable while having excellent mechanical properties.

The present invention relates to polymers, compositions thereof, and methods of producing polymers in general. Furthermore, the present invention relates to pharmaceutical compositions and uses of said polymers, compositions and pharmaceutical compositions. More particular, the present invention relates to polymers of jasmine lactone, where pendant groups of said polymers can readily be used for attaching functional moieties comprising active agents. Furthermore, the present invention relates to modified jasmine lactones that can readily be used in methods of producing polymers of the present invention. More particular, the invention relates to polymers from renewable monomers, which can be used in applications such as drug delivery and diagnosis, polymer-drug conjugates, medical devices, cosmetic products, polymers with marker unit, polymers usable as flame retardants, tissue engineering, coatings, paints, lubricants and biodegradable plastics.