A method for separating a double metal cyanide catalyst (DMC catalyst) from polyol, comprising: A) initially charging a polyol comprising DMC catalyst, an alcohol, and optionally a filtration aid into a reactor, the mixture being heated, B) filtering the mixture from step A), and C) optionally separating the alcohol from the filtrate of step B), wherein in step A), as the alcohol, 4% by weight to 12% by weight of ethanol, based on 100% by weight of polyol, without a chelating agent is used.

The present invention relates to the purification of poloxamers to be used as cell culture media additives. Activated carbon can be used to remove hydrophobic high molecular weight components which reduce the efficacy of poloxamers as cell culture additives.

The present invention relates to the purification of poloxamers to be used as cell culture media additives. Activated carbon can be used to remove hydrophobic high molecular weight components which reduce the efficacy of poloxamers as cell culture additives.

The present invention provides, among other things, methods for preparing functionalized and other polymers from polymer alcohols such as poly(ethylene glycol)s. In addition, polymer compositions, conjugates, polymeric reagents, are also provided.

The present invention provides, among other things, methods for preparing functionalized and other polymers from polymer alcohols such as poly(ethylene glycol)s. In addition, polymer compositions, conjugates, polymeric reagents, are also provided.

The present disclosure relates to a method for preparing a polyalkylene carbonate. More specifically, provided is a method for preparing a polyalkylene carbonate in which after polymerization of polyalkylene carbonate, a mixture from which unreacted carbon dioxide and residual catalyst have been removed is charged into a stripper to remove the unreacted epoxide compound, and then heat-exchanged before removing the solvent to increase the temperature of the mixture stream to the maximum level, which is subjected to a heating step, following by a solvent removal step, whereby the amount of steam required in the heating step is reduced, side reactions due to unreacted epoxide compounds are prevented, and steam energy can be reduced in the solvent removal step.

The present invention provides a method for producing a maleimide polyethylene glycol lipid, and the method includes a reaction step of deprotecting a maleimide polyethylene glycol lipid having a protective group by heating the maleimide polyethylene glycol lipid having a protective group in a solvent in the presence of silica gel. According to the present invention, a production method of preventing deterioration of a maleimide group and improving a maleimidation rate can be provided.

The invention is related to a method for preparing polyether polyols, wherein the method comprises the steps of: a) providing a crude polyether polyols and a base catalyst; b) mixing the crude polyether polyols mixture with an acid thereby providing a neutralized polyether polyols mixture; c) removing water from the neutralized polyether polyols mixture, thereby providing a dehydrated neutralized polyether polyols mixture comprising polyether polyols and a suspension of the crystallized salts suspended in the polyether polyols; d) separating the polyether polyols from the crystallized salt by filtration resulting in a filtration cake comprising crystallized salts and remaining polyether polyols around the crystals; e) removing polyether polyols from the filter, leaving a filtration cake; f) redissolving the filtration cake obtaining a mixture of a salt solution and the remaining polyether polyols; and separating and removing the remaining polyether polyols from the salt solution.

The invention is related to a method for preparing polyether polyols, wherein the method comprises the steps of: a) providing a crude polyether polyols and a base catalyst; b) mixing the crude polyether polyols mixture with an acid thereby providing a neutralized polyether polyols mixture; c) removing water from the neutralized polyether polyols mixture, thereby providing a dehydrated neutralized polyether polyols mixture comprising polyether polyols and a suspension of the crystallized salts suspended in the polyether polyols; d) separating the polyether polyols from the crystallized salt by filtration resulting in a filtration cake comprising crystallized salts and remaining polyether polyols around the crystals; e) removing polyether polyols from the filter, leaving a filtration cake; f) redissolving the filtration cake obtaining a mixture of a salt solution and the remaining polyether polyols; and separating and removing the remaining polyether polyols from the salt solution.

The present invention aims to provide a method of producing a polyether polyol having a low aldehyde content, the method including simpler steps; and a method of producing polyurethane foam having a reduced amount of aldehyde volatilization. The present invention provides a method of producing a polyether polyol (F) including step (1) of obtaining a crude polyether polyol composition (D2) having a pH higher than 5.0 by contact of a crude polyether polyol composition (D1) containing a polyether polyol (A) with an acid catalyst (B) in the presence of water, the polyether polyol (A) being obtainable by ring-opening polymerization of an alkylene oxide with an active hydrogen compound; and step (2) of removing a volatile component containing an aldehyde (C) after step (1).