Patent classifications
A01N63/40
LYSIN CF-301 RESENSITIZES METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUA (MRSA) TO PENICILLIN DERIVATIVES AND FIRST GENERATION CEPHALOSPORINS
Disclosed are methods of resensitizing a Gram-positive bacterium in a subject to at least one β-lactam antibiotic, comprising co-administering the Gram-positive bacterium with the at least one β-lactam antibiotic and a lysin polypeptide, thereby resensitizing the Gram-positive bacterium in the subject to the at least one β-lactam antibiotic.
LYSIN CF-301 RESENSITIZES METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUA (MRSA) TO PENICILLIN DERIVATIVES AND FIRST GENERATION CEPHALOSPORINS
Disclosed are methods of resensitizing a Gram-positive bacterium in a subject to at least one β-lactam antibiotic, comprising co-administering the Gram-positive bacterium with the at least one β-lactam antibiotic and a lysin polypeptide, thereby resensitizing the Gram-positive bacterium in the subject to the at least one β-lactam antibiotic.
Anti-viral paints and coatings and articles comprising same
Disclosed herein are material composition formulated for mitigating activity of a virus on a surface of an article. Methods of preparing such a material composition are also disclosed.
Anti-viral paints and coatings and articles comprising same
Disclosed herein are material composition formulated for mitigating activity of a virus on a surface of an article. Methods of preparing such a material composition are also disclosed.
COCKTAIL COMPOSITIONS COMPRISING RESPIRATORY ANTIBACTERIAL PHAGES AND METHODS OF USE THEREOF
The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention is directed to novel bacteriophage strains and cocktails thereof, as well as variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including respiratory infections caused by, e.g., Pseudomonas aeruginosa and/or Klebsiella pneumoniae. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics or other standard and non-standard therapies for respiratory infections.
Chimeric bacteriophage lysin with activity against staphylococci bacteria
The present disclosure relates to chimeric bacteriophage lysins useful for the identification and/or reduction of staphylococcal populations. For example, a chimeric bacteriophage lysin was engineered and shown to effectively kill all strains of staphylococci tested including antibiotic resistant methicillin-resistant S. aureus (MRSA) and vancomycin intermediate S. aureus (VISA).
Chimeric bacteriophage lysin with activity against staphylococci bacteria
The present disclosure relates to chimeric bacteriophage lysins useful for the identification and/or reduction of staphylococcal populations. For example, a chimeric bacteriophage lysin was engineered and shown to effectively kill all strains of staphylococci tested including antibiotic resistant methicillin-resistant S. aureus (MRSA) and vancomycin intermediate S. aureus (VISA).
Biocompatible siloxanes for formulation of microorganisms
Compositions containing at least one siloxane and at least one active microbiological ingredient are useful for the treatment of plants, of seeds or of soils, as biostimulant or as probiotic food supplement or animal feed additive, or as probiotic medicament. In addition, the siloxane improves the storage stability of an active microbiological ingredient.
Biocompatible siloxanes for formulation of microorganisms
Compositions containing at least one siloxane and at least one active microbiological ingredient are useful for the treatment of plants, of seeds or of soils, as biostimulant or as probiotic food supplement or animal feed additive, or as probiotic medicament. In addition, the siloxane improves the storage stability of an active microbiological ingredient.
NOVEL STREPTOCOCCUS SUIS BACTERIOPHAGE STR-SUP-2, AND USE THEREOF FOR INHIBITING PROLIFERATION OF STREPTOCOCCUS SUIS STRAINS
The present invention relates to a Siphoviridae bacteriophage Str-SUP-2 (Accession number: KCTC 13515BP) isolated from nature and characterized by having the ability to kill Streptococcus suis and having the genome represented by SEQ ID NO: 1, and a method for preventing and treating diseases caused by Streptococcus suis using the composition containing the Siphoviridae bacteriophage Str-SUP-2 as an active ingredient.