The present invention provides a composition comprising: a polyester base polymer; an oxidizable polyether-based additive; a transition metal catalyst; a colorant; and a polyunsaturated fatty ester additives, wherein the polyester base polymer is substantially free of antimony and substantially free of phosphorous. Containers made from the composition are colored and exhibit excellent oxygen scavenging properties with no induction period.

The invention relates to (among other things) oligomer-foscarnet conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered un-conjugated foscarnet compounds.

Disclosed herein is a polyalkylene oxide ester polymer with a weight average molecular weight Mw in the range of from 500 to 50,000 g/mol and a polydispersity PD in the range of from 2 to 6, including 10 to 560 ether groups and 2 to 51 ester groups that are interconnected with alkylene groups, which are significantly more biodegradable than conventional polyalkylene oxide polymers. Further disclosed herein are a method of preparing a polyalkylene oxide ester polymer and a method of using the polyalkylene oxide ester polymer.

Disclosed are compositions, systems and methods related to a polypropiolactone composition comprising polypropiolactone polymers. Such polymers include polypropiolactone chains of Formula (I): where n is an integer from 10 to about 1,000 and Y is either H or a cation. ##STR00001##

A fluoropolymer having fluoropolyether linkages, at least two ester linkages, and hydrolyzable functional groups is represented by chemical structure (I):

##STR00001##

With respect to chemical structure (I), m is a number from 1 to 4 and n is a number from 10 to 60, each R.sup.1 is independently fluorine or CF.sub.3, R.sup.2 is an alkylene group, R.sup.3 is an alkylene group in which one or more hydrogens of the alkylene group are optionally substituted with fluorine, R.sup.4 is an alkyl group in which one or more hydrogens of the alkyl group are substituted with fluorine, R.sup.5 is an alkylene group in which at least one hydrogen of the alkylene group is substituted with a group comprising CF.sub.3, CF.sub.2H, or a hydrolyzable silyl group, and Z is a group represented by chemical structure (II),

##STR00002##

Methods of preparing the fluoropolymer and coating compositions containing the fluoropolymer are also included.

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.

A toughened epoxy resin composition includes an end-capped polyalkylene oxide (A), an epoxy resin (B), an epoxy curing agent (C), and a core shell polymer (D). The end-capped polyalkylene oxide (A) has a number average molecular weight of 1500 to 5000, and 40% or more of a total number of ends of the end-capped polyalkylene oxide (A) are capped with at least one selected from the group consisting of an alkyl group, an allyl group, and an aryl group. A weight ratio of the end-capped polyalkylene oxide (A) to the core shell polymer (D) is 10/90 to 90/10. The core shell polymer (D) comprises a core layer in an amount of 70 to 95% by weight and the core layer is one or more selected from the group consisting of diene rubber, (meth)acrylate rubber, organosiloxane rubber, styrene polymer, and (meth)acrylate polymer.

Vinyl-functional alcohols are silylated by reaction with a hydrolysable silyl hydride compound. The starting alcohol is heated and then combined with the silyl hydride and catalyst and allowed to heat exothermically. Cooling is applied when the conversion of vinyl groups is between 90-99%. In some embodiments, specified amounts of water are present. The cooling regimen and control of water content reduces certain side reactions, leading to greater yields to desired product.

A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The hydrogel structure, which includes photodegradable and thioether moieties in its three dimensional network, enables finely tuned local release of cargo substances as a function of the in vivo tissue environment (e.g., enzyme concentration or reducing environment) and externally applied stimuli (e.g., light) by selective spatiotemporal hydrogel degradation.

The present invention provides an article having a water- and oil-repellent surface layer, as well as excellent water- and oil-repellent properties, abrasion resistance (resistance to abrasion by eraser), and slipperiness, said article being constituted from: a glass substrate; an underlayer formed upon the outer surface of the glass substrate and having a silicon oxide as the main component thereof; and a water- and oil-repellent surface layer formed upon the outer surface of the silicon oxide underlayer. The film density of the silicon oxide underlayer is 1.8-2.2 g/cm.sup.3. The water- and oil-repellent surface layer has, as the main component thereof: a fluoropolyether group-containing polymer having a hydrolyzable silyl group with a specific structure; and/or a cured product of a partially hydrolyzed condensate thereof.