A compound having the formula: ##STR00001## wherein n, y, R.sub.1 and R.sub.2 are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect are described.

(Per)fluoropolyether polymers comprising a (per)fluoropolyether chain having two ends, wherein one or both ends comprise one or more zwitterionic groups at one or both polymer ends, methods for their manufacture and uses thereof are herein disclosed. The polymers can be used in particular for protecting materials in contact with biological fluids or fluids containing biological material from contamination by organic compounds therein contained.

Various embodiments disclosed relate to method of forming organosilicon products. In various embodiments, the present invention provides a method of forming an organosilicon product that can include contacting a first side of a silicone membrane with a nonvolatile liquid reactant. The method can include contacting a second side of the membrane with a gaseous reactant. The contacting can be sufficient to react the gaseous reactant with the liquid reactant to form an organosilicon product on the first side of the silicone membrane. The silicone membrane can be substantially impermeable to the liquid reactant and substantially permeable to the gaseous reactant.

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.

To provide a fluorinated ether compound, a fluorinated ether composition and a coating liquid, capable of forming a surface layer excellent in water/oil repellency, abrasion resistance, fingerprint stain removability, lubricity, chemical resistance and light resistance, as well as an article having such a surface layer. A fluorinated ether compound represented by A.sup.1-O-Q.sup.1-(R.sup.f11O).sub.m1R.sup.f12R.sup.11N[R.sup.12SiR.sup.13.sub.n1X.sup.1.sub.3-n1].sub.2, wherein A.sup.1: C.sub.1-20 perfluoroalkyl group, Q.sup.1: single bond, fluoroalkylene group containing at least one hydrogen atom, etc., R.sup.f11, R.sup.f12: perfluoroalkylene group, m1: integer of from 2 to 200, R.sup.11: single bond, alkylene group, etc., R.sup.12: alkylene group, etc., R.sup.13: monovalent hydrocarbon group, etc., X.sup.1: hydrolyzable group, n1: integer of from 0 to 2.

The invention provides for novel thermo-responsive polymers and compositions comprising the same. In some embodiments, the polymers are water soluble, pH-degradable and have tunable lower critical solution temperatures. Other aspects of the invention include micelles and gels comprising the thermo-responsive polymers and derivatives thereof, as well as methods of delivering therapeutic agents comprising administering a biodegradable gel or micelle comprising a polyacetal compound cross-linked with a linker.

A fluorinated compound having at least one (meth)acrylate functional group disclosed. A curable composition comprising the fluorinated compound and polyfunctional acrylate, a cured product formed from the curable composition, and method of forming the cured product are also disclosed.

Polyethylene glycol substituted acyl borates, methods for their preparation, and the use of the polyethylene glycol substituted acyl borates for the preparation of polyethylene glycol substituted macromolecules. The polyethylene glycol substituted acyl borate has the general formula (I) ##STR00001##
wherein PEG denotes a polyethylene glycol-based substituent; a is an integer from 1 to 12; X1, X2, and X3 are independently of one another selected from the group made of F, OR, N+R3, N+R2OR, N+R2SR, and N+R2NR2, and are optionally forming a cyclic or a bicyclic structure; and R is an organic substituent or H.

The present invention enables the achievement of a coating agent composition which contains a perfluoropolyether compound (A) of a specific structure, and dissolves into at least one volatile organic solvent that does not contain a fluorine atom without using a fluorine-containing solvent having a boiling point of 260 C. or less at atmospheric pressure by setting the content ratio of a non-functional perfluoropolyether compound (B) relative to a total of 100% by mole of the component (A) and the component (B) to less than 2.5% by mole, while forming a cured coating film by being rapidly cured on a base material, said cured coating film firmly adhering to the base material and exhibiting excellent water repellent oil repellent properties, sliding properties, mold releasability and the like.

The present application discloses a low-viscosity silane-terminated resin for a sealant and a preparation method thereof, and belongs to the technical field of sealants. The present application firstly uses an alcohol initiator, an alkaline earth metal and epoxy alkane to synthesize a low-molecular-weight polymer, then adds a polymetallic cyanide catalyst and the epoxy alkane to synthesize a high-molecular-weight polymer, and finally adds carboxylate metal and isocyanate silane to react to obtain the silane-terminated resin. A short chain segment is successfully introduced into a molecule, and an original molecular crystal is destroyed, to achieve intramolecular plasticization, so that its molecular chain becomes flexible and is easy to move, thus the purpose of reducing viscosity is achieved.