An object of the present invention is to provide a method for producing PHA capable of providing PHA (for example, a PHA powder) having excellent thermal stability with high productivity. The present invention is a method for producing polyhydroxyalkanoic acid, the method including a step (a) and a step (b) below: step (a) of preparing an aqueous suspension liquid containing polyhydroxyalkanoic acid and polyvinyl alcohol and having a pH of 7 or less; and step (b) of spray-drying the aqueous suspension liquid prepared in the step (a).

It is provided a microspherical structure comprising an external shell of structured cellulose nanocrystals (CNCs) and at least one polymer, and a core, wherein the core can be hollow or filled with an immiscible medium. It is also provided a method for producing the same comprising spray-drying the mixture of CNCs and polymer through an atomizer and into a drying chamber forming droplets, wherein the solvent used to suspend the CNCs is evaporated and the microspherical structures are formed. These microstructural spheres can have wide industrial, medical and pharmaceutical applications, whereby their ingredients and structure are tuned and controlled.

Disclosed are a sustained-release injection formulation containing a biodegradable polymer microcapsule that contains a conjugate of poly-L-lactic acid (hereinafter referred to as “PLLA”) filler and hyaluronic acid (hereinafter referred to as “HA”) and contains a PLLA-HA microcapsule, and a method of preparing the same.

An anti-environmental stress cracking additive particle, wherein the particle may include an anti-environmental stress cracking active phase, a support phase, and a compatibilizing phase, and wherein the particles have an average size of up to 200 μm. Processes for preparing the anti-environmental stress cracking additive may include a solvent/non-solvent process, a free non-solvent process, and solid state methods. A polymer composition may include a matrix polymer and the anti-environmental stress cracking additive. An article may comprise the polymer composition comprising the anti-environmental stress cracking additive particle.

The invention relates to a gel comprising a first gelatin component and a second gelatin component in an aqueous medium, wherein the first gelatin component comprises gelatin particles comprising chemical cross-links and dehydrothermal cross-links; and the second gelatin component comprises a dissolved gelatin comprising chemical cross-links and at least one polysaccharide.

PCE-type copolymers in powder form can be obtained by spry-drying and are easily re-dispersed in water. The fineness and the anti-caking properties of said PCE-type copolymers in powder form, as well as their water reduction potential and influence on slump life are improved. A production process of said PCE-type copolymers in powder form is by a spray-drying method, and PCE-type copolymers can be used for the improvement of mineral binder compositions and especially dry mortars.

The present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin, and a method for preparing the crosslinked resin. More specifically, the present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin with excellent superhydrophobicity obtained by dual curing of the resin, and a method for preparing the crosslinked resin. The use of the modified siloxane resin according to the present invention allows the crosslinked modified siloxane resin to have excellent superhydrophobicity and high hardness. The water repellency of the crosslinked resin can be appropriately controlled by varying the amount of the siloxane resin mixed.

The present application provides approximately spherical lactic acid-glycolic acid copolymer (PLGA) microparticles comprising a biologically active substance, wherein an average volume-based particle diameter of the PLGA microparticles is 1 μm or more and 150 μm or less, and a Reactive Span Factor (R.S.F.) of the PLGA microparticles is satisfied with formula (1): 0.1<(R.S.F.)≤1.7 formula (1), wherein an R.S.F. means (D90−D10)/D50; D90 is a particle diameter (μm) corresponding to the cumulative 90% by volume of the cumulative particle diameter distribution from the small particle side; D50 is a particle diameter (μm) corresponding to the cumulative 50% by volume of the cumulative particle diameter distribution from the small particle side; and D10 is a particle diameter (μm) corresponding to the cumulative 10% by volume of the cumulative particle diameter distribution from the small particle side; and an efficient production method thereof. The present invention provides the approximately spherical PLGA microparticles having an average volume-based particle diameter of 1 μm or more and 150 μm or less wherein there are few coarse particles or ultrafine particles without a classification step, and the particle diameter distribution is sharp around the target particle diameter.

Disclosed herein are gelatin particles including gelatin, wherein when a major-axis length of dried gelatin particles is defined as a and a major-axis length of gelatin particles after swelling treatment obtained by immersing the dried gelatin particles in water at 40° C. under an atmospheric pressure for 60 minutes is defined as b, swelling degree represented by b/a is 1.0 or more but 10.0 or less, and wherein the gelatin particles after swelling treatment have a particle diameter of 1.0 nm or more but 5.0 μm or less. The gelatin particles are easily taken up by cells themselves.

The present invention provides a hydrophobic alginic acid particle group which is obtained by subjecting a polyvalent metal alginate to a hydrophobization treatment, and which is configured such that the water absorption per 100 g of the particles is lower than the oil absorption per 100 g of the particles.