A method of treating a bacterial infection in a subject includes administering at least a first finely divided (particulate) material, which may have at least a second material, the first material is not bioresorbable or very slowly bioresorable and the second material or materials are bioresorbable at a higher rate than the first material, allowing a certain period of time to pass in order to provide for the first particulate material to be exposed to the body and/or second material or materials to be wholly or partly absorbed by the body of the subject, and administering one or more pharmaceutically active compounds. The first material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds, and the second material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds. The pharmaceutically active compound is a compound capable of treating or ameliorating a bacterial infection.

A method of treating a bacterial infection in a subject includes administering at least a first finely divided (particulate) material, which may have at least a second material, the first material is not bioresorbable or very slowly bioresorable and the second material or materials are bioresorbable at a higher rate than the first material, allowing a certain period of time to pass in order to provide for the first particulate material to be exposed to the body and/or second material or materials to be wholly or partly absorbed by the body of the subject, and administering one or more pharmaceutically active compounds. The first material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds, and the second material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds. The pharmaceutically active compound is a compound capable of treating or ameliorating a bacterial infection.

The invention relates to systems and techniques for manufacturing articles containing cellulosic material, a coupling agent, and a binder resin, and related processes of making and using the cellulosic articles. In particularly exemplary embodiments, the manufactured articles are door skins, sometimes known as door facings, and doors made from the door skins. The article contains a lipophilic cellulosic material, a coupling agent, and a binder. The coupling agent is believed to increase the hydrophilicity (wettability) of the lipophilic cellulosic material.

The invention relates to systems and techniques for manufacturing articles containing cellulosic material, a coupling agent, and a binder resin, and related processes of making and using the cellulosic articles. In particularly exemplary embodiments, the manufactured articles are door skins, sometimes known as door facings, and doors made from the door skins. The article contains a lipophilic cellulosic material, a coupling agent, and a binder. The coupling agent is believed to increase the hydrophilicity (wettability) of the lipophilic cellulosic material.

A detergent-free decellularized ECM preparation method, a detergent-free decellularized ECM in a powder form and in a liquid form, a method of preparation of a primary bioink, the primary bioink, a method of preparation of a vascular bioink, the vascular bioink, a three dimensional structure including the primary bioink and/or the vascular bioink and a method of preparation of the three-dimensional structure.

A detergent-free decellularized ECM preparation method, a detergent-free decellularized ECM in a powder form and in a liquid form, a method of preparation of a primary bioink, the primary bioink, a method of preparation of a vascular bioink, the vascular bioink, a three dimensional structure including the primary bioink and/or the vascular bioink and a method of preparation of the three-dimensional structure.

A negative electrode of a nonaqueous electrolyte secondary battery, which is provided with a collector and a negative electrode active material layer that is formed on the collector, and which is characterized in that: the negative electrode active material layer contains a carbon-based negative electrode active material, a silicon-based negative electrode active material, a conductive agent and a predetermined carboxy methylcellulose or a salt thereof; the content of the carboxy methylcellulose or a salt thereof is from 4% by mass to 15% by mass (inclusive) relative to the total mass of the negative electrode active material layer; and the content of the silicon-based negative electrode active material relative to the total content of the carbon-based negative electrode active material and the silicon-based negative electrode active material is from 3% by mass to 19% by mass (inclusive).

A negative electrode of a nonaqueous electrolyte secondary battery, which is provided with a collector and a negative electrode active material layer that is formed on the collector, and which is characterized in that: the negative electrode active material layer contains a carbon-based negative electrode active material, a silicon-based negative electrode active material, a conductive agent and a predetermined carboxy methylcellulose or a salt thereof; the content of the carboxy methylcellulose or a salt thereof is from 4% by mass to 15% by mass (inclusive) relative to the total mass of the negative electrode active material layer; and the content of the silicon-based negative electrode active material relative to the total content of the carbon-based negative electrode active material and the silicon-based negative electrode active material is from 3% by mass to 19% by mass (inclusive).

A configuration in which an upper auxiliary layer of an absorber includes a super absorbent nonwoven fabric having a surface exposed on an uppermost surface of the absorber and having a Klemm water absorptiveness of 100 mm or more, first super absorbent polymer particles adjacent to a back surface of the super absorbent nonwoven fabric. The main absorption layer of the absorber is a cell absorbing sheet including second super absorbent polymer particles contained in the cells arranged at intervals. A convex bulging upward is formed at each cell in an upper sheet. The first super absorbent polymer particles are fixed to the upper surface of the upper sheet. An adhesion amount of the first super absorbent polymer particles on the upper surface of the upper sheet increases from the top of a convex toward the bottom of a valley between a convex and a convex adjacent each other.

A configuration in which an upper auxiliary layer of an absorber includes a super absorbent nonwoven fabric having a surface exposed on an uppermost surface of the absorber and having a Klemm water absorptiveness of 100 mm or more, first super absorbent polymer particles adjacent to a back surface of the super absorbent nonwoven fabric. The main absorption layer of the absorber is a cell absorbing sheet including second super absorbent polymer particles contained in the cells arranged at intervals. A convex bulging upward is formed at each cell in an upper sheet. The first super absorbent polymer particles are fixed to the upper surface of the upper sheet. An adhesion amount of the first super absorbent polymer particles on the upper surface of the upper sheet increases from the top of a convex toward the bottom of a valley between a convex and a convex adjacent each other.