The present invention provides absorbent materials comprising a hydrogel-forming swellable polymer and a plasticizer, wherein the absorbent material demonstrates an advantageous performance characteristic such as advantageous fluid absorption capacity, fluid absorption rate, and rewetting, wherein the advantageous performance characteristic is within at least about 80% of a similar characteristic exhibited by a crosslinked polyacrylate superabsorbent polymer, or wherein the cumulative performance of the advantageous performance characteristics is comparable or superior to performance exhibited by the crosslinked polyacrylate superabsorbent polymer. The present invention also relates to articles of manufacture comprising such absorbent materials, and methods of manufacture.

Compositions and methods for wound care or the dressing or treatment of wounds in a subject in need thereof. The compositions include an oil-based carrier, a polar solvent comprising one or more polar antimicrobial agents, and collagen or a collagen-based material. In at least some instances, the polar solvent comprising the one or more polar antimicrobial agents and the collagen or collagen-based material are suspended in the oil-based carrier.

Compositions and methods for wound care or the dressing or treatment of wounds in a subject in need thereof. The compositions include an oil-based carrier, a polar solvent comprising one or more polar antimicrobial agents, and collagen or a collagen-based material. In at least some instances, the polar solvent comprising the one or more polar antimicrobial agents and the collagen or collagen-based material are suspended in the oil-based carrier.

The present invention relates to a porous biocompatible implant and a method for manufacturing the same, and more specifically to a porous biocompatible implant in which osseointegration is excellent, no dissociation from the implant occurs, the inflammatory response caused by metals or bacteria can be minimized, and it is possible to accelerate bone formation, while having excellent mineralized bone formation performance, and a method for manufacturing the same. In addition, the porous biocompatible implant of the present invention can be widely used in clinical practices such as dentistry and orthopedic surgery.

The present invention relates to a porous biocompatible implant and a method for manufacturing the same, and more specifically to a porous biocompatible implant in which osseointegration is excellent, no dissociation from the implant occurs, the inflammatory response caused by metals or bacteria can be minimized, and it is possible to accelerate bone formation, while having excellent mineralized bone formation performance, and a method for manufacturing the same. In addition, the porous biocompatible implant of the present invention can be widely used in clinical practices such as dentistry and orthopedic surgery.

Described herein are bioink compositions, which may have an elastic modulus similar to a natural tissue and/or tunable mechanical properties, along with methods of preparing and using the compositions. The compositions described herein may be useful as a medium for cell and/or tissue culture and/or for bioprinting, but are not limited thereto.

Described herein are bioink compositions, which may have an elastic modulus similar to a natural tissue and/or tunable mechanical properties, along with methods of preparing and using the compositions. The compositions described herein may be useful as a medium for cell and/or tissue culture and/or for bioprinting, but are not limited thereto.

The present invention discloses a braided silk scaffold with adjustable mechanical and degradation properties, and a preparation method and use thereof, belonging to the field of three-dimensional scaffold materials for tendon/ligament repair. The preparation method includes braiding at least one silk strand to form a silk core; placing 1-6 bundles of silk cores in a braiding machine, and braiding at least one layer of silk cladding on the surface of the silk cores to form a silk base frame; removing sericin from the silk base frame; soaking the silk base frame in a collagen solution with a concentration of 3-20 mg/ml, and cross-linking the silk base frame in a vacuum thermal cross-linking machine to obtain the silk scaffold. The braided silk scaffold with adjustable mechanical and degradation properties according to the present invention has good mechanical properties and biocompatibility.

The present invention discloses a braided silk scaffold with adjustable mechanical and degradation properties, and a preparation method and use thereof, belonging to the field of three-dimensional scaffold materials for tendon/ligament repair. The preparation method includes braiding at least one silk strand to form a silk core; placing 1-6 bundles of silk cores in a braiding machine, and braiding at least one layer of silk cladding on the surface of the silk cores to form a silk base frame; removing sericin from the silk base frame; soaking the silk base frame in a collagen solution with a concentration of 3-20 mg/ml, and cross-linking the silk base frame in a vacuum thermal cross-linking machine to obtain the silk scaffold. The braided silk scaffold with adjustable mechanical and degradation properties according to the present invention has good mechanical properties and biocompatibility.

Hyaluronic acid and silk protein fragments based tissue fillers and methods of using the same are provided herein.