Temperature-responsive poly(2-hydroxyethyl methacrylate) (PHEMA) and a preparation method thereof are disclosed. In the preparation method, with a system consisting of benzoyl peroxide (BPO) (an oxidant) and 2-methyl-N-[3-(methyl-phenyl-amino)-propyl]-acrylamide (MPAEMA) or 2-methyl-N-[3-(methyl-phenyl-amino)-propyl]-propionamide (MEMA) (a reducing agent monomer) as a redox initiation system, water and toluene as media, a nonionic surfactant as an emulsifier, and 2-hydroxyethyl methacrylate (HEMA) as a polymerization monomer, polymerization is conducted at room temperature and atmospheric pressure to obtain the PHEMA. An alcohol solution of the PHEMA has an upper critical solution temperature (UCST). The method has the advantages of simple and stable polymerization system, low polymerization cost, easy operation, mild conditions, small impact on the environment, and low energy consumption. Moreover, a molecular weight and UCST of a product are controllable within a specified range.

The disclosure relates to a central venous catheter, preparation method thereof and a medical device having the same. The central venous catheter comprises a tube body and a coating formed on the surface of tube body, coating being formed of a coating composition comprising at least one photosensitive functional compound and at least one photocurable polymer. The central venous catheter of the disclosure can prevent thrombosis, dissolve primary thrombus, and possess super-lubricated surface and firm coating bonding.

The disclosure relates to a central venous catheter, preparation method thereof and a medical device having the same. The central venous catheter comprises a tube body and a coating formed on the surface of tube body, coating being formed of a coating composition comprising at least one photosensitive functional compound and at least one photocurable polymer. The central venous catheter of the disclosure can prevent thrombosis, dissolve primary thrombus, and possess super-lubricated surface and firm coating bonding.

A heat exchanger is provided that is operated in a cooling operation mode in which a region to be heat-exchanged is cooled by the heat exchanger or in a drying operation mode in which the heat exchanger is supplied with wind from a blowing fan. The heat exchanger includes a refrigerant pipe, a cooling fin coupled to the refrigerant pipe, and a hydrophilic coating coated on a surface of the refrigerant pipe or the cooling fin. The hydrophilic coating includes a first type transition metal oxide which becomes acidic by reacting with moisture formed on the refrigerant pipe or the cooling fin to have antimicrobial activity when the heat exchanger is operated in the cooling operation mode, and a second type transition metal oxide or a post-transition metal oxide which has antimicrobial activity when the heat exchanger is operated in the drying operation mode.

A heat exchanger is provided that is operated in a cooling operation mode in which a region to be heat-exchanged is cooled by the heat exchanger or in a drying operation mode in which the heat exchanger is supplied with wind from a blowing fan. The heat exchanger includes a refrigerant pipe, a cooling fin coupled to the refrigerant pipe, and a hydrophilic coating coated on a surface of the refrigerant pipe or the cooling fin. The hydrophilic coating includes a first type transition metal oxide which becomes acidic by reacting with moisture formed on the refrigerant pipe or the cooling fin to have antimicrobial activity when the heat exchanger is operated in the cooling operation mode, and a second type transition metal oxide or a post-transition metal oxide which has antimicrobial activity when the heat exchanger is operated in the drying operation mode.

An object of the present invention is to provide an adhesive capable of suppressing plasticizer transfer while maintaining high adhesive force. An adhesive composition of the present invention includes an acrylic polymer (A) and a crosslinking agent (B). The acrylic polymer (A) has units derived from a (meth)acrylic acid alkyl ester (a1), a (meth)acrylamide monomer (a2), and a carboxyl group-containing (meth)acrylic monomer (a3). The weight-average molecular weight of the acrylic polymer (A) is 1,500,000 or less, and the content of a tackifying resin is less than 10 parts by mass relative to 100 parts by mass of the acrylic polymer (A).

The present invention provides a hydrophilic coating method for contact lens surface, firstly performing a hydration procedure S1 to form a hydrated polymer from a non-hydrated polymer, then sequentially contacting the hydrated polymer with a first solution and a second solution containing a high molecular compound at a specific temperature between 50° C. and 70° C. to complete a first hydration process S2 and a second hydration process S3. A contact lens 1 obtained according to the above procedures has a contact angle ranging from about 30° to 65°, and proteins and lipids are not easily deposited on a surface of the contact lens 1, thereby providing the user with good comfort when wearing.

The present invention provides a hydrophilic coating method for contact lens surface, firstly performing a hydration procedure S1 to form a hydrated polymer from a non-hydrated polymer, then sequentially contacting the hydrated polymer with a first solution and a second solution containing a high molecular compound at a specific temperature between 50° C. and 70° C. to complete a first hydration process S2 and a second hydration process S3. A contact lens 1 obtained according to the above procedures has a contact angle ranging from about 30° to 65°, and proteins and lipids are not easily deposited on a surface of the contact lens 1, thereby providing the user with good comfort when wearing.

The present application provides high solids film coating compositions comprising a water-soluble cellulose ether, hydroxy propyl cellulose (HPC), a poly (N-vinyl pyrrolidone-co-vinyl acetate) copolymer, a film-forming agent based on D-glucose, plasticizer, medium chain triglycerides (MCT) and an anti-tack agent. The invention further provides a process for preparing the above described film coating compositions and method of coating solid substrate with such coating compositions.

The present application provides high solids film coating compositions comprising a water-soluble cellulose ether, hydroxy propyl cellulose (HPC), a poly (N-vinyl pyrrolidone-co-vinyl acetate) copolymer, a film-forming agent based on D-glucose, plasticizer, medium chain triglycerides (MCT) and an anti-tack agent. The invention further provides a process for preparing the above described film coating compositions and method of coating solid substrate with such coating compositions.